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Chemical Compound Review

Neohesperidin     (2S)-7-[(2S,3R,4S,5S,6R)-4,5- dihydroxy-6...

Synonyms: LS-39543, NSC 31048, BRN 0074945, AC1L2JS7, 13241-33-3, ...
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Disease relevance of Neohesperidin


High impact information on Neohesperidin


Biological context of Neohesperidin


Associations of Neohesperidin with other chemical compounds


Analytical, diagnostic and therapeutic context of Neohesperidin

  • Neohesperidin monoglucoside was purified from the reaction mixture by glucoamylase and naringinase treatments, an Amberlite XAD-16 column, a Sephadex LH20 column, and HPLC on an ODS column [8].


  1. Subchronic (13-week) oral toxicity of neohesperidin dihydrochalcone in rats. Lina, B.A., Dreef-van der Meulen, H.C., Leegwater, D.C. Food Chem. Toxicol. (1990) [Pubmed]
  2. Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas. Kawaguchi, K., Mizuno, T., Aida, K., Uchino, K. Biosci. Biotechnol. Biochem. (1997) [Pubmed]
  3. Stereoisomeric separation of flavanones and flavanone-7-O-glycosides by capillary electrophoresis and determination of interconversion barriers. Wistuba, D., Trapp, O., Gel-Moreto, N., Galensa, R., Schurig, V. Anal. Chem. (2006) [Pubmed]
  4. Separation of some chiral flavonoids by microbial cyclosophoraoses and their sulfated derivatives in micellar electrokinetic chromatography. Park, H., Jung, S. Electrophoresis (2005) [Pubmed]
  5. Neohesperidin dihydrochalcone is not a taste enhancer in aqueous sucrose solutions. Kroeze, J.H. Chem. Senses (2000) [Pubmed]
  6. In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes. MacGregor, J.T., Wehr, C.M., Manners, G.D., Jurd, L., Minkler, J.L., Carrano, A.V. Mutat. Res. (1983) [Pubmed]
  7. Liquid chromatography of neohesperidin dihydrochalcone. Schwarzenbach, n.u.l.l. J. Chromatogr. (1976) [Pubmed]
  8. Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. Kometani, T., Nishimura, T., Nakae, T., Takii, H., Okada, S. Biosci. Biotechnol. Biochem. (1996) [Pubmed]
  9. Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous Acid-induced DNA strand breakage, protein degradation, and cell death. Choi, J.M., Yoon, B.S., Lee, S.K., Hwang, J.K., Ryang, R. Biol. Pharm. Bull. (2007) [Pubmed]
  10. Determination of naringin and neohesperidin in orange juice by liquid chromatography with UV detection to detect the presence of grapefruit juice: Collaborative Study. Widmer, W. Journal of AOAC International. (2000) [Pubmed]
  11. Separation of flavanone-7-O-glycoside diastereomers and analysis in citrus juices by multidimensional liquid chromatography coupled with mass spectrometry. Aturki, Z., Brandi, V., Sinibaldi, M. J. Agric. Food Chem. (2004) [Pubmed]
  12. Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China. Lu, Y., Zhang, C., Bucheli, P., Wei, D. Plant foods for human nutrition (Dordrecht, Netherlands) (2006) [Pubmed]
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