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Chemical Compound Review

Orobronze     2,4,4-trimethyl-3- [(1E,3E,5E,7E,9E,11E,13E...

Synonyms: Cantaxanthin, Cantaxanthine, Cantaxanthinn, Canthaxanthin, Canthaxanthine, ...
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High impact information on Canthaxanthin

  • Several herbal medications including canthaxanthine, chamomile, datura, Echinacea purpurea, Ginkgo biloba and liquorice have also been associated with several ocular adverse effects.It is the role of all healthcare professionals to detect, treat and educate the public about adverse reactions to medications as they are an important health problem [1].
  • These observations suggest that further studies should be conducted on humans who ingest canthaxanthine to assess structural and functional alterations, especially in the pigment epithelium [2].
  • On questioning the donors it was found that they had been taking a course of 'Orobronze' (an oral 'bronzing' treatment containing canthaxanthin) [3].

Analytical, diagnostic and therapeutic context of Canthaxanthin


  1. Ocular adverse effects associated with systemic medications : recognition and management. Santaella, R.M., Fraunfelder, F.W. Drugs (2007) [Pubmed]
  2. Canthaxanthine-induced retinal pigment epithelial changes in the cat. Scallon, L.J., Burke, J.M., Mieler, W.F., Kies, J.C., Aaberg, T.M. Curr. Eye Res. (1988) [Pubmed]
  3. Detection of carotenoids in blood donors taking Orobronze: a cautionary note. Gunson, H.H., Merry, A.H., Britton, G., Stratton, F. Clinical and laboratory haematology. (1984) [Pubmed]
  4. Ultrahigh-resolution optical coherence tomography of canthaxanthine retinal crystals. Chan, A., Ko, T.H., Duker, J.S. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye. (2006) [Pubmed]
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