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Chemical Compound Review

Rizaben     2-[[(E)-3-(3,4- dimethoxyphenyl)prop-2...

Synonyms: Tranpro, tranilast, Tranilastum, Rizaben (TN), SureCN29875, ...
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Disease relevance of MK 341


High impact information on MK 341


  1. Localization of the anti-allergic agent tranilast in the urinary bladder of rats as demonstrated by light microscopic radioautography. Nishigaki, T., Momose, Y., Nagata, T. Arzneimittel-Forschung. (1990) [Pubmed]
  2. Selective inhibition of collagen accumulation by N-(3,4-dimethoxycinnamoyl)anthranilic acid (N-5') in granulation tissue. Isaji, M., Nakajoh, M., Naito, J. Biochem. Pharmacol. (1987) [Pubmed]
  3. Inhibitory effect of N-(3,4-dimethoxycinnamoyl)anthranilic acid on release of SRS from alveolar macrophages in vitro. Yasuoka, S., Nii, Y., Ohgushi, F., Fujisawa, K., Kawano, T., Nakanishi, Y., Ozaki, T., Yamashita, T. Jpn. J. Pharmacol. (1986) [Pubmed]
  4. Tranilast inhibits cardiac allograft vasculopathy in association with p21(Waf1/Cip1) expression on neointimal cells in murine cardiac transplantation model. Izawa, A., Suzuki Ji, n.u.l.l., Takahashi, W., Amano, J., Isobe, M. Arterioscler. Thromb. Vasc. Biol. (2001) [Pubmed]
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