Chemical Compound Review:
Flolan (5Z)-5-[(1R,5S,7R,8S)-7- hydroxy-8-[(E,3S)...
Synonyms:
Vasocyclin, epoprostenol, prostacyclin, Epoprostenolum, PG-I2, ...
- Increased cortical cell loss and prolonged hemodynamic depression after traumatic brain injury in mice lacking the IP receptor for prostacyclin. Lundblad, C., Grände, P.O., Bentzer, P. J. Cereb. Blood Flow Metab. (2008)
- Prostaglandin X, the vascular metabolite of arachidonic acid responsible for relaxation of bovine coronary artery strips [proceedings]. Dusting, G.J., Lattimer, N., Moncada, S., Vane, J.R. Br. J. Pharmacol. (1977)
- A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation. Moncada, S., Gryglewski, R.J., Bunting, S., Vane, J.R. Prostaglandins (1976)
- Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation. Bunting, S., Gryglewski, R., Moncada, S., Vane, J.R. Prostaglandins (1976)