Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1NR077 (2Z,4S,4aR,5S,5aR,12aS)-2- (amino-hydroxy...

Synonyms:

Borglund, E. et al., Tempera, G. et al., Tempera, G. et al., Depaolis, A.M. et al.

Tempera, Abbadessa, Bonfiglio, Cammarata, Cianci, Corsello, Raimondi, Ettore, Nicolosi, Furneri,

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Disease relevance of meclocycline

One hundred and six patients with acne vulgaris of the face were treated for 10 weeks with either topical meclocycline sulfosalicylate, topical benzoyl peroxide or both preparations [1].

High impact information on meclocycline

Determination of meclocycline, a tetracycline analogue, in cream formulations by liquid chromatography [2].
Reduction in the presence of leukocytes, vaginal mucosa burning and itching were statistically significant in the group treated with kanamycin with respect to the group treated with meclocycline [3].
In chronological order of enrollment, the patients were alternately treated with kanamycin or meclocycline; the dose of administration in both groups was of one pessary per day for 6 days [4].

Chemical compound and disease context of meclocycline

Topical meclocycline sulfosalicylate, benzoyl peroxide, and a combination of the two in the treatment of acne vulgaris [1].

References

Topical meclocycline sulfosalicylate, benzoyl peroxide, and a combination of the two in the treatment of acne vulgaris. Borglund, E., Kristensen, B., Larsson-Stymne, B., Strand, A., Veien, N.K., Jakobsen, H.B. Acta Derm. Venereol. (1991) [Pubmed]
Determination of meclocycline, a tetracycline analogue, in cream formulations by liquid chromatography. Depaolis, A.M., Britt, T.E., Holman, A.J., McGonigle, E.J., Kaplan, G., Davies, W.C. Journal of pharmaceutical sciences. (1984) [Pubmed]
Topical kanamycin: an effective therapeutic option in aerobic vaginitis. Tempera, G., Abbadessa, G., Bonfiglio, G., Cammarata, E., Cianci, A., Corsello, S., Raimondi, A., Ettore, G., Nicolosi, D., Furneri, P.M. Journal of chemotherapy (Florence, Italy) (2006) [Pubmed]
Microbiological/clinical characteristics and validation of topical therapy with kanamycin in aerobic vaginitis: a pilot study. Tempera, G., Bonfiglio, G., Cammarata, E., Corsello, S., Cianci, A. Int. J. Antimicrob. Agents (2004) [Pubmed]

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