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Chemical Compound Review

CHEBI:60634     methyl 2-[(3S,5S)-5-[[4-[4-(N'...

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Disease relevance of Lefradafiban


High impact information on Lefradafiban


  1. Safety and preliminary efficacy of one month glycoprotein IIb/IIIa inhibition with lefradafiban in patients with acute coronary syndromes without ST-elevation; a phase II study. Akkerhuis, K.M., Neuhaus, K.L., Wilcox, R.G., Vahanian, A., Boland, J.L., Hoffmann, J., Baardman, T., Nehmiz, G., Roth, U., Klootwijk, A.P., Deckers, J.W., Simoons, M.L. Eur. Heart J. (2000) [Pubmed]
  2. Profound and sustained inhibition of platelet aggregation by Fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men. Müller, T.H., Weisenberger, H., Brickl, R., Narjes, H., Himmelsbach, F., Krause, J. Circulation (1997) [Pubmed]
  3. Absorption of lefradafiban from different sites of the gastrointestinal tract. Drewe, J., Narjes, H., Heinzel, G., Brickl, R.S., Rohr, A., Beglinger, C. British journal of clinical pharmacology. (2000) [Pubmed]
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