The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Midafotee     4-[(E)-3-phosphonoprop-2- enyl]piperazine-2...

Synonyms: Cppene, CHEMBL224678, SureCN726553, LS-172816, LS-172991, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of D-Cpp-ene

 

High impact information on D-Cpp-ene

 

Gene context of D-Cpp-ene

  • The present study sought to evaluate the analgesic potency of combined administration of morphine (5-20 mg/kg) and a competitive NMDA receptor antagonist D-CPPene (SDZ EAA 494; 3-(2-carboxypiperazin-4-yl)-1-propenyl-1-phosphonic acid; 0.3-5.6 mg/kg) in the tail-flick and tail-pinch tests with rats [5].

References

  1. Focal ischemic damage is reduced by CPP-ene studies in two animal models. Bullock, R., McCulloch, J., Graham, D.I., Lowe, D., Chen, M.H., Teasdale, G.M. Stroke (1990) [Pubmed]
  2. The pharmacology of SDZ EAA 494, a competitive NMDA antagonist. Lowe, D.A., Emre, M., Frey, P., Kelly, P.H., Malanowski, J., McAllister, K.H., Neijt, H.C., Rüdeberg, C., Urwyler, S., White, T.G. Neurochem. Int. (1994) [Pubmed]
  3. Electrical but not chemical kindling increases sensitivity to some phencyclidine-like behavioral effects induced by the competitive NMDA receptor antagonist D-CPPene in rats. Wlaź, P., Ebert, U., Potschka, H., Löscher, W. Eur. J. Pharmacol. (1998) [Pubmed]
  4. Focal cerebral ischemia in the cat: pretreatment with a competitive NMDA receptor antagonist, D-CPP-ene. Bullock, R., Graham, D.I., Chen, M.H., Lowe, D., McCulloch, J. J. Cereb. Blood Flow Metab. (1990) [Pubmed]
  5. Prolongation of morphine analgesia by competitive NMDA receptor antagonist D-CPPene (SDZ EAA 494) in rats. Bespalov, A., Kudryashova, M., Zvartau, E. Eur. J. Pharmacol. (1998) [Pubmed]
  6. The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy. Sveinbjornsdottir, S., Sander, J.W., Upton, D., Thompson, P.J., Patsalos, P.N., Hirt, D., Emre, M., Lowe, D., Duncan, J.S. Epilepsy Res. (1993) [Pubmed]
 
WikiGenes - Universities