Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

DL-Xylose (2R,3S,4R)-2,3,4,5- tetrahydroxypentanal

Synonyms: D-Xyl, S2124_Selleck, BIFS0118, CHEBI:15936, ANW-33057, ...

Govinden, R. et al., Metzger, M.H. et al.

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High impact information on xylose

The mutagenized XYL2 gene could still mediate growth of Saccharomyces cerevisiae transformants on xylose minimal-medium plates when expressed together with the xylose reductase gene (XYL1) [1].
The xylose reductase gene (XYL1) was isolated from Pichia stipitis and Candida shehatae, cloned into YEp-based vectors under the control of ADH2 and PGK1 promoter/terminator cassettes and introduced into Saccharomyces cerevisiae Y294 by electroporation [2].

References

Amino acid substitutions in the yeast Pichia stipitis xylitol dehydrogenase coenzyme-binding domain affect the coenzyme specificity. Metzger, M.H., Hollenberg, C.P. Eur. J. Biochem. (1995) [Pubmed]
Xylitol production by recombinant Saccharomyces cerevisiae expressing the Pichia stipitis and Candida shehatae XYL1 genes. Govinden, R., Pillay, B., van Zyl, W.H., Pillay, D. Appl. Microbiol. Biotechnol. (2001) [Pubmed]

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