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Chemical Compound Review:

T Acid 8-aminonaphthalene-1,3,6- trisulfonic acid

Synonyms: Amino-H acid, AG-F-86266, Koch acid, CHEBI:340596, NSC-227195, ...

Ellens, H. et al., Cabrera, G. et al., Klockow, A. et al., Stack, R.J. et al., Gennaro, L.A. et al.

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High impact information on Koch acid

The kinetics of release were measured continuously by using the water-soluble fluorophore 8-aminonaphthalene-1,3,6-trisulfonic acid in combination with the water-soluble quencher p- xylylenebis (pyridinium) bromide [1].
Electrophoretic resolution and fluorescence detection of N-linked glycoprotein oligosaccharides after reductive amination with 8-aminonaphthalene-1,3,6-trisulphonic acid [2].
Glycosylation profiling was performed by labelling the N-glycans released by peptide N-glycosidase F with either of the fluorophore tags 8-aminonaphthalene-1,3,6-trisulphonic acid and 4-aminobenzoic acid [3].

Analytical, diagnostic and therapeutic context of Koch acid

The influence of buffer composition on separation efficiency and resolution in capillary electrophoresis of 8-aminonaphthalene-1,3,6-trisulfonic acid labeled monosaccharides and complex carbohydrates [4].
Among charged labels which have shown promise in assisting CE and HPLC separation is the fluorophore 8-aminonaphthalene-1,3,6-trisulfonic acid (ANTS) [5].

References

pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact. Ellens, H., Bentz, J., Szoka, F.C. Biochemistry (1984) [Pubmed]
Electrophoretic resolution and fluorescence detection of N-linked glycoprotein oligosaccharides after reductive amination with 8-aminonaphthalene-1,3,6-trisulphonic acid. Stack, R.J., Sullivan, M.T. Glycobiology (1992) [Pubmed]
Influence of culture conditions on the N-glycosylation of a monoclonal antibody specific for recombinant hepatitis B surface antigen. Cabrera, G., Cremata, J.A., Valdés, R., García, R., González, Y., Montesino, R., Gómez, H., González, M. Biotechnol. Appl. Biochem. (2005) [Pubmed]
The influence of buffer composition on separation efficiency and resolution in capillary electrophoresis of 8-aminonaphthalene-1,3,6-trisulfonic acid labeled monosaccharides and complex carbohydrates. Klockow, A., Amado, R., Widmer, H.M., Paulus, A. Electrophoresis (1996) [Pubmed]
Capillary electrophoresis/electrospray ion trap mass spectrometry for the analysis of negatively charged derivatized and underivatized glycans. Gennaro, L.A., Delaney, J., Vouros, P., Harvey, D.J., Domon, B. Rapid Commun. Mass Spectrom. (2002) [Pubmed]

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