Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AmbotzHAA8080 2-amino-3-(6-chloro-1H-indol- 3...

Synonyms: SureCN623336, AG-E-28322, KB-199371, AKOS016011219, FT-0621066, ...

Heyes, M.P. et al., Saito, K. et al.

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High impact information on Tryptophan, 6-chloro-

Inhibitors of the kynurenine pathway, 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilic acid, attenuated [13C6]QUIN formation by macrophages, and when co-infused with [13C6]L-tryptophan into poliovirus-infected macaques [1].
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells) [2].

References

A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate. Heyes, M.P., Saito, K., Major, E.O., Milstien, S., Markey, S.P., Vickers, J.H. Brain (1993) [Pubmed]
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells). Saito, K., Chen, C.Y., Masana, M., Crowley, J.S., Markey, S.P., Heyes, M.P. Biochem. J. (1993) [Pubmed]

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