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Chemical Compound Review

s-Butanol     butan-2-ol

Synonyms: sec-Butanol, s-Butylalkohol, D-sec-Butanol, L-sec-Butanol, Butanol-2, ...
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Disease relevance of NSC25499

  • The crystal structure of a thermophilic alcohol dehydrogenase (TBAD) from Thermoanaerobacter brockii has been determined in a binary complex with sec-butanol as substrate to a resolution of 3.0 A [1].
  • Over a period of 10 years, 20 spina bifida occulta (S.B.O.) and 22 spina bifida aperta (S.B.A.) patients were operated [2].

High impact information on NSC25499


Anatomical context of NSC25499


Analytical, diagnostic and therapeutic context of NSC25499

  • Pigments extracted with sec-butanol were indistinguishable from those extracted using acetone as determined by quantitative and qualitative HPLC [5].


  1. Crystal structure of a thermophilic alcohol dehydrogenase substrate complex suggests determinants of substrate specificity and thermostability. Li, C., Heatwole, J., Soelaiman, S., Shoham, M. Proteins (1999) [Pubmed]
  2. Tethered cord syndrome: clinical signs and results of operation in 42 patients with spina bifida aperta and occulta. Begeer, J.H., Wiertsema, G.P., Breukers, S.M., Mooy, J.J., ter Weeme, C.A. Zeitschrift für Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft für Kinderchirurgie = Surgery in infancy and childhood. (1989) [Pubmed]
  3. Effect of temperature and concentration on the structure of sec-butyl alcohol and isobutyl alcohol/water mixtures: near-infrared spectroscopic study. Wojtków, D., Czarnecki, M.A. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory. (2006) [Pubmed]
  4. Apparent equilibration time required for surfactant-oil-water systems to emulsify into the morphology imposed by the formulation. Part 2: Effect of sec-butanol concentration and initial location. Alvarez, G., Antón, R., Marfisi, S., Márquez, L., Salager, J.L. Langmuir : the ACS journal of surfaces and colloids. (2004) [Pubmed]
  5. One-step extraction and concentration of pigments and acyl lipids by sec-butanol from in vitro and in vivo samples. Martinson, T.A., Plumley, F.G. Anal. Biochem. (1995) [Pubmed]
  6. A Crystallite Packing Model for Pseudoboehmite Formed during the Hydrolysis of Trisecbutoxyaluminium to Explain the Peptizability. Martens, W.N., Kloprogge, J.T., Frost, R.L., Bartlett, J.R. Journal of colloid and interface science. (2002) [Pubmed]
  7. Sensory irritation, pulmonary irritation and structure-activity relationships of alcohols. Hansen, L.F., Nielsen, G.D. Toxicology (1994) [Pubmed]
  8. Cranial venous system and the posterior fossa in spina bifida aperta. Blaauw, G. Clinical neurology and neurosurgery. (1975) [Pubmed]
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