Disease relevance of Fermentation butyl alcohol

• The hydrophobia of the penicillins was characterized by determination of their partition coefficients between isobutanol and buffer solution pH 7 [1].
• Abnormally increased concentrations of the aliphatic alcohols ethanol, n-propanol, isobutanol, n-butanol and isopentanol and the ketones 4-heptanone and cyclohexanone in human urine reflect metabolic disorders related to diabetes mellitus [2].
• Location by paper chromatography of compensatory ovarian hypertrophy (COH) inhibiting activity in isobutanol extracts of bovine pineals [3].
• 3-Methyl-1-butanol (MEB) and 2-methyl-1-propanol (MEP) were tested for their prenatal inhalation toxicity in pregnant Wistar rats or Himalayan rabbits [4].

High impact information on Fermentation butyl alcohol

• The second route, via pyruvate decarboxylase, is the one that is used because elimination of pyruvate decarboxylase activity in a pdc1 pdc5 pdc6 triple mutant virtually abolished isobutyl alcohol production [5].
• The metabolism of valine to isobutyl alcohol in yeast was examined by 13C nuclear magnetic resonance spectroscopy and combined gas chromatography-mass spectrometry [5].
• In this procedure for disopyramide in serum, the drug is extracted into n-heptane/isobutanol (96/4 by vol), then back-extracted into 1 mol/L H2SO4 [6].
• Before mass spectrometry analysis, glutamine and glutamic acid are derivatized with dimethylformamide dimethyl acetal and isobutanol to form dimethylformamidine isobutyl ester [7].
• Reactions in isobutyl alcohol afford the Friedel-Crafts alkylation adducts in excellent yields and with up to +98% ee [8].

Biological context of Fermentation butyl alcohol

• On applying enzymic hydrolysis in combination with isobutanol extraction, the mean concentration was eight times higher than that obtained when using extraction only [9].
• In this study, the pharmacokinetics of a major organic nitrite inhalant, isobutyl nitrite (ISBN), and its primary metabolite, isobutyl alcohol (ISBA), were investigated after inhalation and i.v. administration [10].
• Small quantities of isobutanol were produced by most of the strains and higher amounts by some S. cerevisiae strains with phenotypes Gal- and Mel-; all S. bayanus strains produced low amounts of amilyc alcohols [11].
• It depends on the phosphorylation of the substrates with [gamma-32P]ATP, hydrolysis of the pyrophosphate bonds by boiling in 1 N HCl, extraction of 32P with isobutanol-benzene, and measurement of the radioactivity of 32P-labeled phosphoesters in the water phase [12].
• The kinetics of ampicillin and amoxicillin partitioning with simultaneous acid-catalyzed hydrolysis were studied in a stirred transfer cell containing isobutanol as the extract and aqueous hydrochloric acid (0.1-0.5 N) as the raffinate at 37 degrees [13].

Anatomical context of Fermentation butyl alcohol

• The two enzymes separate on ion exchange chromatography of an isobutanol extract of intestinal brush border membrane fraction [14].
• Astrocytes were also found to inactivate rapidly isobutanol-extracted ANTA in normal K+-containing growth medium [15].
• Although P is directly related to K in both olive oil and isobutanol systems, the bile duct behaves as if its permeability barrier is more hydrophilic than isobutanol [16].
• From these results we thus have concluded that paint thinner taken can be proved by detecting the presence of ethyl acetate and isobutanol together with toluene in the stomach, whereas only toluene can be detected in the body fluids and the other tissue [17].

Associations of Fermentation butyl alcohol with other chemical compounds

• P. mirabilis and K. pneumoniae typically showed three intense peaks which corresponded to isobutanol, isopentyl acetate and isopentanol [18].
• The volatiles were identified by concurrent headspace concentration-gas chromatography-mass spectrometry and consisted mainly of isobutanol, isopentanol, isopentyl acetate, 1-undecene and methyl ketones [18].
• The effect of temperature and concentration on the structure of sec-butyl alcohol and isobutyl alcohol/water binary mixtures in the alcohol-rich region (mole fraction of water X(H2O) < 0.3) has been studied using Fourier transform (FT) near-infrared (NIR) spectroscopy [19].
• Biexponential data for the concentration in both the raffinate (C1) and the extract (C2) as a function of time were analyzed simultaneously by nonlinear regression to estimate the apparent first-order rate constant for transfer from hydrochloric acid to isobutanol (k '12), the reverse transfer constant (k '21), and the hydrolysis rate constant (k) [13].
• These biofilms, after inoculation with P. viridicatum, produced offensive smelling alcohols and esters such as 2-methyl propanol, 3-penten-2-ol, and the ethyl ester of butanoic acid [20].
• Ethanol, n-butanol, and isobutanol response networks were compared. n-Butanol and isobutanol responses were qualitatively similar, whereas ethanol had notable induction differences of pspABCDE and ndh, whose gene products manage proton motive force [21].

Gene context of Fermentation butyl alcohol

• On the other hand, it can be concluded that the eca40 mutation has a drastic effect on the production of isobutanol [22].
• Methanol and isobutanol influenced the variability in PC1, which led to discrimination [23].
• Butanol was the best modifier for benalaxyl; isobutanol was the best modifier for lactofen, malathion, diclofop-methyl, and ethofumesate; and IPA was the best modifier for the other five [24].

Analytical, diagnostic and therapeutic context of Fermentation butyl alcohol

• The reaction mixture was extracted with isobutanol and subjected to HPLC monitored by a fluorescent detector [25].
• The MDA-TBA complex formed was extracted with isobutyl alcohol and measured by high-performance liquid chromatography with fluorescence detection [26].
• Isobutanol soluble COH-inhibiting activity was further separated by chromatography on Sephadex G-15 and paper chromatography [3].
• The addition of the alcohol iso-butanol (2-methylpropan-1-ol) to water was found to improve the post-staining procedures for semi-thin and ultrathin resin sections, for both light and electron microscopy [27].
• Solution-grown chain-folded lamellar single crystals of poly(tetramethylene adipate) (PTMA) were prepared from a dilute solution of 2-methyl-1-propanol by isothermal crystallization [28].

References