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Chemical Compound Review:

NovoNorm 2-ethoxy-4-[[(1S)-3-methyl-1- [2-(1...

Synonyms: Surepost, Actulin, GlucoNorm, Prandin, Repaglinida, ...

Plosker, G.L. et al., Kalliokoski, A. et al., Greischel, A. et al., Ampudia-Blasco, F.J. et al.

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Disease relevance of Repaglinide

Repaglinide (Prandin), NovoNorm, GlucoNorm, an oral insulin secretagogue, was the first meglitinide analogue to become available for use in patients with type 2 diabetes mellitus [1].

High impact information on Repaglinide

Comparative dose-related time-action profiles of glibenclamide and a new non-sulphonylurea drug, AG-EE 623 ZW, during euglycaemic clamp in healthy subjects [2].

Associations of Repaglinide with other chemical compounds

While on gemfibrozil, the minimum blood glucose concentration after repaglinide intake was 19% lower in the c.521CC participants than in the c.521TT participants (P = 0.009) [3].

Analytical, diagnostic and therapeutic context of Repaglinide

Quantitation of the new hypoglycaemic agent AG-EE 388 ZW in human plasma by automated high-performance liquid chromatography with electrochemical detection [4].

References

Repaglinide : a pharmacoeconomic review of its use in type 2 diabetes mellitus. Plosker, G.L., Figgitt, D.P. PharmacoEconomics. (2004) [Pubmed]
Comparative dose-related time-action profiles of glibenclamide and a new non-sulphonylurea drug, AG-EE 623 ZW, during euglycaemic clamp in healthy subjects. Ampudia-Blasco, F.J., Heinemann, L., Bender, R., Schmidt, A., Heise, T., Berger, M., Starke, A.A. Diabetologia (1994) [Pubmed]
Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism. Kalliokoski, A., Backman, J.T., Kurkinen, K.J., Neuvonen, P.J., Niemi, M. Clin. Pharmacol. Ther. (2008) [Pubmed]
Quantitation of the new hypoglycaemic agent AG-EE 388 ZW in human plasma by automated high-performance liquid chromatography with electrochemical detection. Greischel, A., Beschke, K., Rapp, H., Roth, W. J. Chromatogr. (1991) [Pubmed]

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