Disease relevance of Atranorine

• Airborne contact dermatitis from atranorin [1].
• Hemolysis induced by pannarin and 1'chloropannarin increases in the presence of oxygen, whereas hemolysis induced by atranorin is higher in nitrogen-purged solutions [2].

High impact information on Atranorine

• Identification of atranorin and related potential allergens in oakmoss absolute by high-performance liquid chromatography-tandem mass spectrometry using negative ion atmospheric pressure chemical ionization [3].
• Our first results showed that atranol and chloroatranol, formed by transesterification and decarboxylation of the lichen depsides, atranorin and chloroatranorin, during the preparation of oak moss absolute, are strong elicitants in most patients sensitized to oak moss [4].
• Methyl beta-orcinolcarboxylate (2), ethyl hematommate (3), the didepside atranorin (4), and (+)-protolichesterinic acid (7) did not influence keratinocyte growth at concentrations of 5 microM [5].
• Atranorin was the only lichen acid with no significant effect on ATPase [6].

Analytical, diagnostic and therapeutic context of Atranorine

• Thin-layer chromatography and a spot test indicated that atranorin is present in oak moss perfumes which are made from oak moss and tree moss [7].
• Atranorin, one of the most common lichen substances, gave positive patch test reactions in eight subjects (1%) in a routine series [7].

References