High impact information on Fmrfamide

• By contrast, eya regulates Fmrf expression by controlling both axon pathfinding and BMP signaling, but cannot trigger Fmrf ectopically [1].
• Coexistence of FMRFAMIDE-like and LHRH-like immunoreactivity in the terminal nerve and forebrain of the big brown bat, Eptesicus fuscus [2].
• Whereas in most areas of the prosencephalon (e.g., stria terminalis and bed nuclei, amygdaloid complex) fibers show stronger immunoreactivity to FMRFAMIDE, labeling of fibers in the habenula and infundibulum is largely identical for both neuropeptides [2].
• In contrast to LHRH immunoreactivity, FMRFAMIDE-like ir extends throughout the brainstem and cervical spinal cord [2].
• The arcuate nucleus contains a large number of perikarya and is the major source of both FMRFAMIDE- and LHRH-ir within the forebrain [2].

Biological context of Fmrfamide

• Localization of fmrfamide-like immunoreactivity in the peripheral organs and its cross reaction with neuropeptide Y in the rat [3].

Gene context of Fmrfamide

• Fmrf expression is controlled by a combinatorial code of intrinsic factors and an extrinsic BMP signal [1].

Analytical, diagnostic and therapeutic context of Fmrfamide

• The coexistence of molluscan cardioexcitatory neuropeptide (FMRFAMIDE) and luteinizing hormone-releasing hormone (LHRH) was studied in the nervous system of the big brown bat, Eptesicus fuscus, with immunocytochemistry [2].

References