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Chemical Compound Review

Diamant     2-(1-methyl-2,3,4,5- tetrahydropyrrol-1-yl)...

Synonyms: Diaspasmol, Diaspasmyl, Diospasmyl, Propyromazine, LD-335, ...
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Disease relevance of Diaspasmol

  • An episode of parasitic enteritis causing trickling mortalities at an exhibition aquarium reproducing Mediterranean ecosystems was found to be caused by the myxozoan parasite Myxidium leei Diamant, Lom & Dykova 1994 [1].

High impact information on Diaspasmol

  • We found that the Al concentration in the hair of control subjects was not related to sex or hair color and that there was a highly significant (P less than 0.001) difference between values for control subjects and hemodialyzed patients: 126 (SD 58) nmol/g, n = 49, vs 226 (SD 104) nmol/g, n = 39, respectively [2].
  • A significant reduction in diastolic blood pressure occurred (mean +/- SD 104 +/- 6 vs 92 +/- 3; p < 0.05); renal function improved or stabilized in over 80% of patients [3].

Analytical, diagnostic and therapeutic context of Diaspasmol


  1. Myxidium leei (Myxozoa) infections in aquarium-reared Mediterranean fish species. Padrós, F., Palenzuela, O., Hispano, C., Tosas, O., Zarza, C., Crespo, S., Alvarez-Pellitero, P. Dis. Aquat. Org. (2001) [Pubmed]
  2. Analytical problems encountered in determining aluminum status from hair in controls and hemodialyzed patients. Chappuis, P., Duhaux, L., Paolaggi, F., de Vernejoul, M.C., Rousselet, F. Clin. Chem. (1988) [Pubmed]
  3. Renal artery stenting in patients with a solitary functioning kidney. Cioni, R., Vignali, C., Petruzzi, P., Neri, E., Caramella, D., Vagli, P., Bargellini, I., Napoli, V., Pinto, S., Bartolozzi, C. Cardiovascular and interventional radiology. (2001) [Pubmed]
  4. Phenotypic and genotypic risk factors for cardiovascular events in an incident dialysis cohort. Pernod, G., Bosson, J.L., Golshayan, D., Barro, C., Forneris, G., Martina, G., Bonfant, G., Hurot, J.M., Turc-Baron, C., Jouet, C., Theytaz, J., Jeantet, A., Wauters, J.P., Cordonnier, D. Kidney Int. (2006) [Pubmed]
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