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Chemical Compound Review:

Diamant 2-(1-methyl-2,3,4,5- tetrahydropyrrol-1-yl)...

Synonyms: Diaspasmol, Diaspasmyl, Diospasmyl, Propyromazine, LD-335, ...

This record was replaced with 71494.

Chappuis, P. et al., Padrós, F. et al., Cioni, R. et al., Pernod, G. et al.

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Disease relevance of Diaspasmol

An episode of parasitic enteritis causing trickling mortalities at an exhibition aquarium reproducing Mediterranean ecosystems was found to be caused by the myxozoan parasite Myxidium leei Diamant, Lom & Dykova 1994 [1].

High impact information on Diaspasmol

We found that the Al concentration in the hair of control subjects was not related to sex or hair color and that there was a highly significant (P less than 0.001) difference between values for control subjects and hemodialyzed patients: 126 (SD 58) nmol/g, n = 49, vs 226 (SD 104) nmol/g, n = 39, respectively [2].
A significant reduction in diastolic blood pressure occurred (mean +/- SD 104 +/- 6 vs 92 +/- 3; p < 0.05); renal function improved or stabilized in over 80% of patients [3].

Analytical, diagnostic and therapeutic context of Diaspasmol

The 279 patients (244 on hemodialysis, 35 on peritoneal dialysis) within the Diamant Alpin Dialysis Cohort Study were investigated [4].

References

Myxidium leei (Myxozoa) infections in aquarium-reared Mediterranean fish species. Padrós, F., Palenzuela, O., Hispano, C., Tosas, O., Zarza, C., Crespo, S., Alvarez-Pellitero, P. Dis. Aquat. Org. (2001) [Pubmed]
Analytical problems encountered in determining aluminum status from hair in controls and hemodialyzed patients. Chappuis, P., Duhaux, L., Paolaggi, F., de Vernejoul, M.C., Rousselet, F. Clin. Chem. (1988) [Pubmed]
Renal artery stenting in patients with a solitary functioning kidney. Cioni, R., Vignali, C., Petruzzi, P., Neri, E., Caramella, D., Vagli, P., Bargellini, I., Napoli, V., Pinto, S., Bartolozzi, C. Cardiovascular and interventional radiology. (2001) [Pubmed]
Phenotypic and genotypic risk factors for cardiovascular events in an incident dialysis cohort. Pernod, G., Bosson, J.L., Golshayan, D., Barro, C., Forneris, G., Martina, G., Bonfant, G., Hurot, J.M., Turc-Baron, C., Jouet, C., Theytaz, J., Jeantet, A., Wauters, J.P., Cordonnier, D. Kidney Int. (2006) [Pubmed]

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