The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Cohort Studies

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Cohort Studies


Psychiatry related information on Cohort Studies


High impact information on Cohort Studies


Chemical compound and disease context of Cohort Studies


Biological context of Cohort Studies


Anatomical context of Cohort Studies


Associations of Cohort Studies with chemical compounds

  • DESIGN: Retrospective cohort study with serum folate levels measured from September 1970 to December 1972, with follow-up through 1985 [31].
  • DESIGN--Retrospective analysis of data from a prospective cohort study of patients treated with zidovudine [32].
  • DESIGN AND SETTING: Retrospective cohort study conducted at 2 anticoagulation clinics based in Seattle, Wash. PARTICIPANTS: Two hundred patients receiving long-term warfarin therapy for various indications during April 3, 1990, to May 31, 2001 [33].
  • DESIGN--Cross-sectional analysis of homocysteine levels and vitamin blood levels and intake in elderly participants in the Framingham Study. SETTING--Population-based cohort in Framingham, Mass. PARTICIPANTS--A total of 1160 adult survivors, aged 67 to 96 years, from the original Framingham Heart Study cohort [34].
  • DESIGN, SETTING, AND PARTICIPANTS--The design was a prospective cohort study using data from the Physicians' Health Study, a randomized trial of aspirin and beta carotene among 22,071 US male physicians aged 40 to 84 years that began in 1982 [35].

Gene context of Cohort Studies

  • Moreover, R60S, a mutation in the first intracellular loop of CCR5 noted in a recent cohort study, likewise results in reduced surface expression and function of CCR5 [36].
  • This study investigates the influence of genetic variation of the estrogen receptor alpha (ESR1) gene locus on several bone parameters in 2042 individuals of The Rotterdam Study, a prospective population-based cohort study of elderly subjects [37].
  • Concurrent studies of Sm/IGF stimulation of 3H-thymidine incorporation revealed that these cells were most sensitive to Sm-C/IGF I, followed by IGF II and MSA, and insulin [38].
  • MATERIALS AND METHODS: We analyzed four variants of LRP5 and one amino acid variant of the LRP6 gene in a large prospective population-based cohort study of elderly subjects [39].
  • We conducted an association study between common polymorphisms in CLCN7 and haplotypes defined by these polymorphisms and BMD values at the lumbar spine and femoral neck in a population-based cohort study of 1077 Scottish women 45-55 years of age [40].

Analytical, diagnostic and therapeutic context of Cohort Studies


  1. The effect of epilepsy or diabetes mellitus on the risk of automobile accidents. Hansotia, P., Broste, S.K. N. Engl. J. Med. (1991) [Pubmed]
  2. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. Lakka, H.M., Laaksonen, D.E., Lakka, T.A., Niskanen, L.K., Kumpusalo, E., Tuomilehto, J., Salonen, J.T. JAMA (2002) [Pubmed]
  3. Risk of end-stage renal disease in diabetes mellitus: a prospective cohort study of men screened for MRFIT. Multiple Risk Factor Intervention Trial. Brancati, F.L., Whelton, P.K., Randall, B.L., Neaton, J.D., Stamler, J., Klag, M.J. JAMA (1997) [Pubmed]
  4. Pneumococcal vaccine. Efficacy and associated cost savings. Gable, C.B., Holzer, S.S., Engelhart, L., Friedman, R.B., Smeltz, F., Schroeder, D., Baum, K. JAMA (1990) [Pubmed]
  5. Risk of chronic arthropathy among women after rubella vaccination. Vaccine Safety Datalink Team. Ray, P., Black, S., Shinefield, H., Dillon, A., Schwalbe, J., Holmes, S., Hadler, S., Chen, R., Cochi, S., Wassilak, S. JAMA (1997) [Pubmed]
  6. The relation of glycaemia to the risk of development and progression of retinopathy in the Diabetic Control and Complications Trial. Service, F.J., O'Brien, P.C. Diabetologia (2001) [Pubmed]
  7. Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease? Hashimoto, M., Kazui, H., Matsumoto, K., Nakano, Y., Yasuda, M., Mori, E. The American journal of psychiatry. (2005) [Pubmed]
  8. Dementia and Alzheimer disease incidence: a prospective cohort study. Kukull, W.A., Higdon, R., Bowen, J.D., McCormick, W.C., Teri, L., Schellenberg, G.D., van Belle, G., Jolley, L., Larson, E.B. Arch. Neurol. (2002) [Pubmed]
  9. Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder? Campo, J.V., Dahl, R.E., Williamson, D.E., Birmaher, B., Perel, J.M., Ryan, N.D. Journal of the American Academy of Child and Adolescent Psychiatry. (2003) [Pubmed]
  10. Psychosocial Work Environment and Incidence of Severe Depressive Symptoms: Prospective Findings from a 5-Year Follow-up of the Danish Work Environment Cohort Study. Rugulies, R., Bültmann, U., Aust, B., Burr, H. Am. J. Epidemiol. (2006) [Pubmed]
  11. Effect of the use or nonuse of long-term dialysis on the subsequent survival of renal transplants from living donors. Mange, K.C., Joffe, M.M., Feldman, H.I. N. Engl. J. Med. (2001) [Pubmed]
  12. The risk of menstrual abnormalities after tubal sterilization. U.S. Collaborative Review of Sterilization Working Group. Peterson, H.B., Jeng, G., Folger, S.G., Hillis, S.A., Marchbanks, P.A., Wilcox, L.S. N. Engl. J. Med. (2000) [Pubmed]
  13. Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. Early Postmenopausal Intervention Cohort Study Group. Hosking, D., Chilvers, C.E., Christiansen, C., Ravn, P., Wasnich, R., Ross, P., McClung, M., Balske, A., Thompson, D., Daley, M., Yates, A.J. N. Engl. J. Med. (1998) [Pubmed]
  14. Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fingerhut, M.A., Halperin, W.E., Marlow, D.A., Piacitelli, L.A., Honchar, P.A., Sweeney, M.H., Greife, A.L., Dill, P.A., Steenland, K., Suruda, A.J. N. Engl. J. Med. (1991) [Pubmed]
  15. Malignant thyroid tumors after iodine-131 therapy: a retrospective cohort study. Holm, L.E., Dahlqvist, I., Israelsson, A., Lundell, G. N. Engl. J. Med. (1980) [Pubmed]
  16. Serum alpha-tocopherol and subsequent risk of lung cancer among male smokers. Woodson, K., Tangrea, J.A., Barrett, M.J., Virtamo, J., Taylor, P.R., Albanes, D. J. Natl. Cancer Inst. (1999) [Pubmed]
  17. Intake of carotenoids and retinol in relation to risk of prostate cancer. Giovannucci, E., Ascherio, A., Rimm, E.B., Stampfer, M.J., Colditz, G.A., Willett, W.C. J. Natl. Cancer Inst. (1995) [Pubmed]
  18. Risk of pneumonitis in breast cancer patients treated with radiation therapy and combination chemotherapy with paclitaxel. Taghian, A.G., Assaad, S.I., Niemierko, A., Kuter, I., Younger, J., Schoenthaler, R., Roche, M., Powell, S.N. J. Natl. Cancer Inst. (2001) [Pubmed]
  19. Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study. Graham, N.M., Zeger, S.L., Park, L.P., Phair, J.P., Detels, R., Vermund, S.H., Ho, M., Saah, A.J. Lancet (1991) [Pubmed]
  20. COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Ray, W.A., Stein, C.M., Daugherty, J.R., Hall, K., Arbogast, P.G., Griffin, M.R. Lancet (2002) [Pubmed]
  21. Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma. Xu, H.J., Quinlan, D.C., Davidson, A.G., Hu, S.X., Summers, C.L., Li, J., Benedict, W.F. J. Natl. Cancer Inst. (1994) [Pubmed]
  22. Inflammatory bowel disease is not associated with an increased risk of lymphoma. Lewis, J.D., Bilker, W.B., Brensinger, C., Deren, J.J., Vaughn, D.J., Strom, B.L. Gastroenterology (2001) [Pubmed]
  23. Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit. Brun-Buisson, C., Legrand, P., Rauss, A., Richard, C., Montravers, F., Besbes, M., Meakins, J.L., Soussy, C.J., Lemaire, F. Ann. Intern. Med. (1989) [Pubmed]
  24. Plasminogen activator inhibitor 4G polymorphism is associated with decreased risk of cerebrovascular mortality in older women. Roest, M., van der Schouw, Y.T., Banga, J.D., Tempelman, M.J., de Groot, P.G., Sixma, J.J., Grobbee, D.E. Circulation (2000) [Pubmed]
  25. Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study. Freedman, M.L., Pearce, C.L., Penney, K.L., Hirschhorn, J.N., Kolonel, L.N., Henderson, B.E., Altshuler, D. Am. J. Hum. Genet. (2005) [Pubmed]
  26. Development of a simplified single-apheresis approach for peripheral-blood progenitor-cell transplantation in previously treated patients with lymphoma. Jones, H.M., Jones, S.A., Watts, M.J., Khwaja, A., Mills, W., Fielding, A., Goldstone, A.H., Linch, D.C. J. Clin. Oncol. (1994) [Pubmed]
  27. Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens. Ho, H.N., Hultin, L.E., Mitsuyasu, R.T., Matud, J.L., Hausner, M.A., Bockstoce, D., Chou, C.C., O'Rourke, S., Taylor, J.M., Giorgi, J.V. J. Immunol. (1993) [Pubmed]
  28. Clinical and biochemical factors associated with prognosis after myocardial infarction at a young age. Malmberg, K., Båvenholm, P., Hamsten, A. J. Am. Coll. Cardiol. (1994) [Pubmed]
  29. Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study. Singh, G., Ramey, D.R., Morfeld, D., Shi, H., Hatoum, H.T., Fries, J.F. Arch. Intern. Med. (1996) [Pubmed]
  30. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study. Dalton, S.O., Johansen, C., Mellemkjaer, L., Nørgård, B., Sørensen, H.T., Olsen, J.H. Arch. Intern. Med. (2003) [Pubmed]
  31. Serum folate and risk of fatal coronary heart disease. Morrison, H.I., Schaubel, D., Desmeules, M., Wigle, D.T. JAMA (1996) [Pubmed]
  32. Differential survival of patients with AIDS according to the 1987 and 1993 CDC case definitions. Vella, S., Chiesi, A., Volpi, A., Giuliano, M., Floridia, M., Dally, L.G., Binkin, N. JAMA (1994) [Pubmed]
  33. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. Higashi, M.K., Veenstra, D.L., Kondo, L.M., Wittkowsky, A.K., Srinouanprachanh, S.L., Farin, F.M., Rettie, A.E. JAMA (2002) [Pubmed]
  34. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. Selhub, J., Jacques, P.F., Wilson, P.W., Rush, D., Rosenberg, I.H. JAMA (1993) [Pubmed]
  35. A prospective study of cigarette smoking and risk of cataract in men. Christen, W.G., Manson, J.E., Seddon, J.M., Glynn, R.J., Buring, J.E., Rosner, B., Hennekens, C.H. JAMA (1992) [Pubmed]
  36. A homologous naturally occurring mutation in Duffy and CCR5 leading to reduced receptor expression. Tamasauskas, D., Powell, V., Saksela, K., Yazdanbakhsh, K. Blood (2001) [Pubmed]
  37. Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. van Meurs, J.B., Schuit, S.C., Weel, A.E., van der Klift, M., Bergink, A.P., Arp, P.P., Colin, E.M., Fang, Y., Hofman, A., van Duijn, C.M., van Leeuwen, J.P., Pols, H.A., Uitterlinden, A.G. Hum. Mol. Genet. (2003) [Pubmed]
  38. Characterization of somatomedin/insulin-like growth factor receptors and correlation with biologic action in cultured neonatal rat astroglial cells. Han, V.K., Lauder, J.M., D'Ercole, A.J. J. Neurosci. (1987) [Pubmed]
  39. Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men. van Meurs, J.B., Rivadeneira, F., Jhamai, M., Hugens, W., Hofman, A., van Leeuwen, J.P., Pols, H.A., Uitterlinden, A.G. J. Bone Miner. Res. (2006) [Pubmed]
  40. Polymorphisms of the CLCN7 gene are associated with BMD in women. Pettersson, U., Albagha, O.M., Mirolo, M., Taranta, A., Frattini, A., McGuigan, F.E., Vezzoni, P., Teti, A., van Hul, W., Reid, D.M., Villa, A., Ralston, S.H. J. Bone Miner. Res. (2005) [Pubmed]
  41. The effect of parental history of myopia on children's eye size. Zadnik, K., Satariano, W.A., Mutti, D.O., Sholtz, R.I., Adams, A.J. JAMA (1994) [Pubmed]
  42. Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers. Stolzenberg-Solomon, R.Z., Albanes, D., Nieto, F.J., Hartman, T.J., Tangrea, J.A., Rautalahti, M., Sehlub, J., Virtamo, J., Taylor, P.R. J. Natl. Cancer Inst. (1999) [Pubmed]
  43. Cholesterol screening in asymptomatic adults, revisited. Part 2. Garber, A.M., Browner, W.S., Hulley, S.B. Ann. Intern. Med. (1996) [Pubmed]
  44. Predictors of virological response in HIV-infected patients to salvage antiretroviral therapy that includes nelfinavir. Walmsley, S.L., Becker, M.I., Zhang, M., Humar, A., Harrigan, P.R. Antivir. Ther. (Lond.) (2001) [Pubmed]
  45. Retrospective analysis of utilization patterns and cost implications of coxibs among seniors in Quebec, Canada: what is the potential impact of the withdrawal of rofecoxib? Rahme, E., Hunsche, E., Toubouti, Y., Chabot, I. Arthritis Rheum. (2006) [Pubmed]
WikiGenes - Universities