Disease relevance of Accent

• Monitoring and effects of nicosulfuron in aquatic mesocosms: development of a simple analytical procedure and evidence for low toxicity to phytoplankton communities [1].

High impact information on Accent

• Nicosulfuron: alcoholysis, chemical hydrolysis, and degradation on various minerals [2].
• The endpoints used to assess sensitivity to atrazine and nicosulfuron were total biomass increase, photosynthetic efficiency, and community diversity, depending on the system considered [3].
• We have tested the sensitivity of phytoplankton to the herbicides atrazine and nicosulfuron in experiments conduced in increasingly complex systems, from single strain phytoplankton cultures (microplates) to mesocosms mimicking whole ecosystems [3].
• Comparison study of this test indicated that the mode of action of monosulfuron was the same as that of other sulfonylurea herbicides such as chlorsulfuron, tribenuron-methyl and nicosulfuron, they were all inhibitors targeted at the ALS [4].
• For example, the diatoms inside the community were not affected by atrazine and nicosulfuron, except for Stephanodiscus minutulus that was sensitive to both, and Asterionella/formosa that was sensitive only to nicosulfuron [5].

Associations of Accent with other chemical compounds

• Monosulfuron was a good acetolactate synthase (ALS) inhibitor in vitro, the I50 (50% of inhibition) of monosulfuron, chlorsulfuron, tribenuron-methyl and nicosulfuron for CAU 3138 were 32, 2, 19 and 26 nmol/L respectively, for Yedan 13 the I50 were 15, 3, 17 and 65 nmol/L respectively [4].

Gene context of Accent

• Atrazine and nicosulfuron have different targets in plant metabolism, respectively, photosystem II (PSII) and acetolactate synthase (ALS), and the expected effects were different [5].

References