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Chemical Compound Review

Trilixon     1-(2-chlorophenyl)sulfonyl-3- (4-methoxy-6...

Synonyms: Finesse, Khardin, Chlorsulfon, Glean, Telar, ...
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Disease relevance of Chlorsulphuron


High impact information on Chlorsulphuron

  • A deleted, nonfunctional fragment from the acetolactate synthase gene, carrying the mutant site specifying chlorsulfuron resistance plus a closely linked novel restriction site marker, was cloned into a binary vector [1].
  • The ALS gene encoding acetolactase synthase, which confers resistance to chlorsulfuron, functioned as a versatile marker for selection of plants grown in tissue culture as well as in soil [6].
  • Furthermore, foliar application of chlorsulfuron confirmed the development of resistant phenotypes [7].
  • Here we report crystal structures of yeast AHAS in complex with chlorsulfuron (at a resolution of 2.19 A), sulfometuron methyl (2.34 A), and two other sulfonylureas, metsulfuron methyl (2.29 A) and tribenuron methyl (2.58 A) [8].
  • Inhibition by both herbicides exhibits slow-binding kinetics, whereas chlorsulphuron also shows tight-binding inhibition [9].

Biological context of Chlorsulphuron


Anatomical context of Chlorsulphuron

  • We also conclude that for those who like to preserve the saphenous vein, the preferential use of polytetrafluoroethylene or Dacron Hemashield Finesse patching may be appropriate [14].
  • MATERIAL AND METHODS: A total of 64 ceramic bars were formed to produce 4 groups of 16 bars each for 4 ceramic materials (Duceram-LFC Dentin, Duceram-LFC Enamel, Finesse Dentin, and Finesse Enamel) [12].
  • Results showed that mixtures of herbicides with similar molecular targets, i.e. chlorsulfuron and metsulfuron (acetolactate synthase (ALS) inhibitors), and with different molecular targets, i.e. pendimethalin (microtubule assembly inhibitor) and pretilachlor (very long chain fatty acids (VLCFAs) inhibitor), followed the ADM [15].

Associations of Chlorsulphuron with other chemical compounds

  • Phenylurea herbicides were indirectly determined in the form of their derived anilines and chlorsulfuron in the form of an aminotriazine as confirmed by gas chromatography-mass spectrometry [16].
  • In the sulfonylurea-resistant background, which derives from herbicide-resistant acetolactate synthase activity, induction of the In2-2 promoter by chlorsulfuron was lower [17].
  • This work analyzes carbohydrate concentration in sources and sinks after herbicide treatments in pea (Pisum sativum L.), as well as photosynthetic carbon assimilation, using two classes of chemicals, chlorsulfuron and imazethapyr, applied to roots or leaves [18].
  • OBJECTIVES: This study sought to evaluate the efficacy of using an X-ray diffractometer for the determination of leucite in Finesse, Ceramco II, and IPS Empress porcelains [19].
  • Three different selection agents (kanamycin, chlorsulfuron and imazethapyr) were tested for in vitro selection efficiency in two B. juncea cultivars, RLM198 and Varuna [20].

Gene context of Chlorsulphuron

  • Acetolactate synthase extracted from the two biotypes was equally sensitive to both ethametsulfuron-methyl and chlorsulfuron [21].
  • METHODS: Six porcelains were tested: A (Ceramco I/Dentsply), B (Ceramco II/Dentsitply), C (Finesse/Dentsply), D (d.Sign/Ivoclar), Cb (Cerabien/Noritake) and V (Vitadur Alpha/Vita) [22].
  • At the time of the survey in 1985, products containing prespruf and 1,1,1-trichloro-2,2-bis (p-chlorophenyl)ethane (DDT) were the most popular insecticide, and products containing diquat, diclofop-methyl, chlorsulfuron and glyphosate as active ingredients represented the four most popular herbicides [23].

Analytical, diagnostic and therapeutic context of Chlorsulphuron

  • Chlorsulfuron-resistant plants were regenerated from calli after mesophyll protoplast electroporation or leaf tissue particle bombardment with these specifically constructed chimeras [7].
  • For gynecologic electrosurgery, the Aspen Sabre 180 and Laserscope e10 were rated best, followed closely by the Utah Finesse and Finesse II and the Gyne-Tech Autolepe 4000 [24].
  • Determination of chlorsulfuron residues in grain, straw, and green plants of cereals by high-performance liquid chromatography [25].
  • CONCLUSION: The results indicate that the bond strengths of stainless steel orthodontic brackets bonded to Finesse and Empress II porcelains are clinically acceptable [26].
  • A study was performed to compare the positioning reproducibility and the cost efficiency for two head and neck immobilization devices: the Uvex (Uvex Safety, Smithfield, USA) plastic mask system and the Finesse Frame with Ultraplast System (PLANET Medical, Svendborg, Denmark) [4].


  1. Homologous recombination in plant cells after Agrobacterium-mediated transformation. Lee, K.Y., Lund, P., Lowe, K., Dunsmuir, P. Plant Cell (1990) [Pubmed]
  2. Effect of chlorsulfuron on growth of submerged aquatic macrophyte Potamogeton pectinatus (sago pondweed). Coyner, A., Gupta, G., Jones, T. Environ. Pollut. (2001) [Pubmed]
  3. Biodegradation of chlorsulfuron and metsulfuron-methyl by Aspergillus niger. Zanardini, E., Negri, M., Boschin, G., D'Agostina, A., Valle, A., Arnoldi, A., Sorlini, C. ScientificWorldJournal (2002) [Pubmed]
  4. A comparative evaluation of two head and neck immobilization devices using electronic portal imaging. Donato, K., Leszczynski, K., Fleming, K. The British journal of radiology. (2006) [Pubmed]
  5. Inheritance and expression of chimeric genes in the progeny of transgenic maize plants. Fromm, M.E., Morrish, F., Armstrong, C., Williams, R., Thomas, J., Klein, T.M. Biotechnology (N.Y.) (1990) [Pubmed]
  6. High-frequency germinal transposition of DsALS in Arabidopsis. Honma, M.A., Baker, B.J., Waddell, C.S. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  7. Chimeric RNA/DNA oligonucleotide-based site-specific modification of the tobacco acetolactate syntase gene. Kochevenko, A., Willmitzer, L. Plant Physiol. (2003) [Pubmed]
  8. Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. McCourt, J.A., Pang, S.S., Guddat, L.W., Duggleby, R.G. Biochemistry (2005) [Pubmed]
  9. Expression, purification and characterization of Arabidopsis thaliana acetohydroxyacid synthase. Chang, A.K., Duggleby, R.G. Biochem. J. (1997) [Pubmed]
  10. Fitness consequences of genetically engineered herbicide and antibiotic resistance in Arabidopsis thaliana. Purrington, C.B., Bergelson, J. Genetics (1997) [Pubmed]
  11. Bioavailability of bound residue derived from 14C-labeled chlorsulfuron in soil and its mechanism of phytotoxicity. Ye, Q.F., Wu, J.M., Sun, J.H. Journal of environmental sciences (China). (2004) [Pubmed]
  12. Effects of acid hydrolysis and mechanical polishing on surface residual stresses of low-fusing dental ceramics. Alkhiary, Y.M., Morgano, S.M., Giordano, R.A. The Journal of prosthetic dentistry. (2003) [Pubmed]
  13. Capillary column gas chromatographic determination of trace residues of the herbicide chlorsulfuron in agricultural runoff water. Ahmad, I. Journal - Association of Official Analytical Chemists. (1987) [Pubmed]
  14. Patch closure improves results with carotid endarterectomy. Aburahma, A.F. Seminars in vascular surgery. (2004) [Pubmed]
  15. Activities of mixtures of soil-applied herbicides with different molecular targets. Kaushik, S., Streibig, J.C., Cedergreen, N. Pest Manag. Sci. (2006) [Pubmed]
  16. Indirect analysis of urea herbicides from environmental water using solid-phase microextraction. Berrada, H., Font, G., Moltó, J.C. Journal of chromatography. A. (2000) [Pubmed]
  17. Herbicide safener-inducible gene expression in Arabidopsis thaliana. De Veylder, L., Van Montagu, M., Inzé, D. Plant Cell Physiol. (1997) [Pubmed]
  18. Carbohydrate accumulation in leaves of plants treated with the herbicide chlorsulfuron or imazethapyr is due to a decrease in sink strength. Zabalza, A., Orcaray, L., Gaston, S., Royuela, M. J. Agric. Food Chem. (2004) [Pubmed]
  19. Quantification of leucite concentration using X-ray diffraction. Ong, J.L., Farley, D.W., Norling, B.K. Dental materials : official publication of the Academy of Dental Materials. (2000) [Pubmed]
  20. Mutant acetolactate synthase gene is an efficient in vitro selectable marker for the genetic transformation of Brassica juncea (oilseed mustard). Ray, K., Jagannath, A., Gangwani, S.A., Burma, P.K., Pental, D. J. Plant Physiol. (2004) [Pubmed]
  21. Metabolism-based resistance of a wild mustard (Sinapis arvensis L.) biotype to ethametsulfuron-methyl. Veldhuis, L.J., Hall, L.M., O'Donovan, J.T., Dyer, W., Hall, J.C. J. Agric. Food Chem. (2000) [Pubmed]
  22. Correlation between fracture toughness and leucite content in dental porcelains. Cesar, P.F., Yoshimura, H.N., Miranda Júnior, W.G., Okada, C.Y. Journal of dentistry. (2005) [Pubmed]
  23. Patterns of pesticide usage by cereal crop farmers in Western Australia. Spickett, J.T., Dolin, P.J., Phillips, M.R., Priestley, C.J. Asia-Pacific journal of public health / Asia-Pacific Academic Consortium for Public Health. (1989) [Pubmed]
  24. Gynecologic and dermatologic electrosurgical units: a comparative review. Ferris, D.G., Saxena, S., Hainer, B.L., Searle, J.R., Powell, J.L., Gay, J.N. The Journal of family practice. (1994) [Pubmed]
  25. Determination of chlorsulfuron residues in grain, straw, and green plants of cereals by high-performance liquid chromatography. Slates, R.V. J. Agric. Food Chem. (1983) [Pubmed]
  26. Comparison of the bond strength of stainless steel orthodontic brackets bonded to crown porcelains. Chay, S.H., Wattanapayungkul, P., Yap, A.U., Loh, P.L., Chung, S.M. Australian orthodontic journal. (2005) [Pubmed]
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