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Chemical Compound Review:

Metazene dodecyl 2-methylprop-2-enoate

Synonyms: LAMA, Sipomer LMA, NSC-5188, AG-D-84939, Ageflex FM 246, ...

Rakovska, A. et al., Haigh, R. et al., Le Gac, S. et al., Lewis, A.L. et al., Kudo, H. et al.

Lewis, Cumming, Goreish, Kirkwood, Tolhurst, Stratford,

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High impact information on LAURYL METHACRYLATE

The biosensor utilizes the physical and chemical functions of hydrophobic polydimethyl siloxane (PDMS) and hydrophilic 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymerized with dodecyl methacrylate (DMA) [1].
However, all compositions of poly(2,3-propandiol-1-methacrylate-co-ethandiol dimethacrylate) (i.e. hydrogels that do not contain dodecyl methacrylate repeat units) were poor substrates for cell growth and examination of these materials showed that very few cells had adhered and those that did were highly rounded [2].
2-Methacryloyloxyethyl phosphorylcholine (MPC) was synthesised and then used in the preparation of crosslinked polymer membranes with lauryl methacrylate, hydroxypropyl methacrylate and trimethoxysilylpropyl methacrylate (crosslinker) comonomers [3].
The LMA-based columns were first prepared in a capillary format using capillary tubing of 75 microm i.d. and tested in nanoLC-MS experiments for the separation of a commercial Cytochrome C digest composed of 12 peptidic fragments whose isoelectric point values and hydrophobic character cover a wide range [4].
Effects of a new cholecystokinin antagonist (GE 410) on the smooth muscle of the guinea pig ileum [5].

Anatomical context of LAURYL METHACRYLATE

GE 410 inhibited the electrically-induced cholinergically mediated contractile responses and the [3H]ACh release in the ileum, as well as the CCK-stimulated electrical contractile responses and the [3H]ACh release in the cholinergic nerve terminals [5].

References

A flexible and wearable glucose sensor based on functional polymers with Soft-MEMS techniques. Kudo, H., Sawada, T., Kazawa, E., Yoshida, H., Iwasaki, Y., Mitsubayashi, K. Biosensors & bioelectronics. (2006) [Pubmed]
Synthesis and properties of amphiphilic networks 2: a differential scanning calorimetric study of poly(dodecyl methacrylate-stat-2,3 propandiol-1-methacrylate-stat-ethandiol dimethacrylate) networks and adhesion and spreading of dermal fibroblasts on these materials. Haigh, R., Fullwood, N., Rimmer, S. Biomaterials (2002) [Pubmed]
Crosslinkable coatings from phosphorylcholine-based polymers. Lewis, A.L., Cumming, Z.L., Goreish, H.H., Kirkwood, L.C., Tolhurst, L.A., Stratford, P.W. Biomaterials (2001) [Pubmed]
Monoliths for microfluidic devices in proteomics. Le Gac, S., Carlier, J., Camart, J.C., Cren-Olivé, C., Rolando, C. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2004) [Pubmed]
Effects of a new cholecystokinin antagonist (GE 410) on the smooth muscle of the guinea pig ileum. Rakovska, A., Milenov, K., Henklein, P. Experientia (1990) [Pubmed]

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