Disease relevance of dimethyl-oxo-silane

• A whole-cell bioassay has been performed using Escherichia coli sensor strains immobilized in a chip assembly, in which a silicon substrate is placed between two poly(dimethylsiloxane) (PDMS) substrates [1].
• Partition controlled delivery of hydrophobic substances in toxicity tests using poly(dimethylsiloxane) (PDMS) films [2].
• Mylicon drops in the treatment of infant colic [3].
• Those trends apparent in polymers synthesized with poly(dimethylsiloxane) or poly(ethylene oxide) soft segments, but poly(dimethylsiloxane)-based materials showed higher levels of thrombus deposition than the poly(ethylene oxide)-based polymers [4].
• Cerebral artery SMC plated on a flexible polydimethyl siloxane membrane showed loss of tension during exposure to hypoxia [5].

Psychiatry related information on dimethyl-oxo-silane

• A series of fibers, 100-microm poly(dimethylsiloxane), 65-microm poly(dimethylsiloxane)/divinylbenzene, and 75-microm Carboxen/poly(dimethylsiloxane), were tested for their "zero sink", face velocity, and response time behavior [6].

High impact information on dimethyl-oxo-silane

• A poly(dimethylsiloxane) stamp, patterned in bas-relief and supporting an 80-nanometer-thick gold film, is brought into contact with an 80-nanometer-thick film of poly(methylmethacrylate) supported on n-doped silicon [7].
• To investigate the participation of TSP2 in the FBR, polydimethylsiloxane (PDMS) and oxidized PDMS (ox-PDMS) disks were implanted in TSP2-null and control mice [8].
• A novel method for the rapid fabrication of poly(methyl methacrylate) (PMMA) microfluidic chips using poly(dimethylsiloxane) (PDMS) templates has been demonstrated [9].
• A single-channel poly(dimethylsiloxane) microchip was developed for the desorption process monitoring and kinetics studies of a single particle [10].
• This theoretical prediction was verified by the experiments, in which melanocytes were exposed to microfabricated poly(dimethylsiloxane) substrates having parallel rectangular grooves of heights (h) between 25 and 200 nm and spatial frequencies (L) between 100 and 500 mm(-1) [11].

Biological context of dimethyl-oxo-silane

• Spatially Controlled Cell Adhesion via Micropatterned Surface Modification of Poly(dimethylsiloxane) [12].
• Oxygen consumption of cell suspension in a poly(dimethylsiloxane) (PDMS) microchannel estimated by scanning electrochemical microscopy [13].
• These MFNs were coated with Au, onto which a hydrophilic, protein-repellent monolayer of thiolated poly(ethyleneglycol) (HS-PEG) was self-assembled, and the binding sites for analytes were present on a poly(dimethylsiloxane) (PDMS) sealing cover [14].
• Distribution of silicon/e in tissues of mice of different fibrinogen genotypes following intraperitoneal administration of emulsified poly(dimethylsiloxane) [correction of poly(dimethysiloxane)] [15].
• This has been achieved by use of a coaxial needle arrangement where a concentrated living biosuspension flows through the inner needle and a medical-grade poly(dimethylsiloxane) (PDMS) medium with high viscosity (12 500 mPa s) and low electrical conductivity (10-15 S m-1) flows through the outer needle [16].

Anatomical context of dimethyl-oxo-silane

• Stable and fluid ethylphosphocholine membranes in a poly(dimethylsiloxane) microsensor for toxin detection in flooded waters [17].
• The concept, called a capillary-assembled microchip, involves embedding chemically functionalized capillaries into a lattice microchannel network fabricated on poly(dimethylsiloxane) (PDMS) [18].
• This paper describes the influence of the composition of poly(dimethylsiloxane) (PDMS) on the attachment and growth of several different types of mammalian cells: primary human umbilical artery endothelial cells (HUAECs), transformed 3T3 fibroblasts (3T3s), transformed osteoblast-like MC3T3-E1 cells, and HeLa (transformed epithelial) cells [19].
• Lipid-gel and poly(dimethylsiloxane) film to mimic bioaccumulation in adipocytes [20].
• Permeation of supersaturated DZP across polydimethylsiloxane (PDMS) membranes, chosen as an in vitro model for nasal mucosa, was shown to be well described by Theeuwes's transference equation, when DZP was formulated up to three times its solubility in a particular cosolvent vehicle [21].

Associations of dimethyl-oxo-silane with other chemical compounds

• Surface modification of the channels of poly(dimethylsiloxane) microfluidic chips with polyacrylamide for fast electrophoretic separations of proteins [22].
• These transfer efficiencies exhibit sensitivities related to the permeation of the poly(dimethylsiloxane) (PDMS) stamp by the silane reagents [23].
• Additionally, the PEMs surface treatment can be used to condition various surfaces, facilitating neuronal cultures on surfaces which are natively hydrophilic (tissue culture polystyrene) or hydrophobic (poly(dimethylsiloxane), PDMS) [24].
• The biosensor utilizes the physical and chemical functions of hydrophobic polydimethyl siloxane (PDMS) and hydrophilic 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymerized with dodecyl methacrylate (DMA) [25].
• The SPME experimental procedures to extract amphetamine and methamphetamine in serum were optimized with a relatively non-polar poly(dimethylsiloxane) coated fiber at pH 9.5, extraction time for 40 min and desorption at 260 degrees C for 2 min [26].

Gene context of dimethyl-oxo-silane

• Expression of matrix metalloproteinase-2 and -9 in exudates associated with polydimethyl siloxane and gelatin tubes implanted in mice [27].
• After a 4-week implantation period, both types of PDMS elicited a similar FBR with a collagenous capsule in both TSP2-null and control mice [8].
• Fractionation of polydispersed polysiloxanes (1-2 g) into narrow molecular weight fractions has been achieved by a rapid (30-60 min) convenient process, using the Cyclograph Centrifugal Chromatography System. These narrow molecular weight poly(dimethylsiloxane) fractions can be used as secondary standards for GPC [28].
• An ESI emitter made of poly(dimethylsiloxane) interfaces on-chip sample preparation with MS detection [29].
• First, single biological cells were trapped, injected, steered, and deposited by means of optical tweezers in a poly(dimethylsiloxane) microfluidic device and consecutively lysed with SDS at a predefined position [30].

Analytical, diagnostic and therapeutic context of dimethyl-oxo-silane

• This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS) [31].
• Simple sealing methods for poly(dimethylsiloxane) (PDMS)/glass-based capillary electrophoresis (CE) microchips by UV irradiation are described [32].
• This paper characterizes this problem as it applies to microfluidic cell culture in poly(dimethylsiloxane) (PDMS) devices and provides a practical solution [33].
• A rigid poly(dimethylsiloxane) sandwich electrophoresis microchip based on thin-casting method [34].
• A miniaturized immunoassay system based on beads in poly(dimethylsiloxane) microchannels for analyzing multiple analytes has been developed [35].

References