Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

adk - adenylate kinase

Escherichia coli CFT073

Bouvier, L.A. et al., Shapiro, Y.E. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of adk

Activation energy of catalysis-related domain motion in E. coli adenylate kinase [1].
In this work, we identified and characterized the adenylate kinase activity in extracts from the flagellated parasite Trypanosoma cruzi, the causative agent of Chagas' disease [2].

High impact information on adk

Adenylate kinase activity was detected in different subcellular fractions and the cytosolic isoform was biochemically characterized [2].

Analytical, diagnostic and therapeutic context of adk

Six different genes of adenylate kinase isoforms were identified and the mRNA expression was confirmed by RT-PCR and Northern Blot [2].

References

Activation energy of catalysis-related domain motion in E. coli adenylate kinase. Shapiro, Y.E., Meirovitch, E. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006) [Pubmed]
An expanded adenylate kinase gene family in the protozoan parasite Trypanosoma cruzi. Bouvier, L.A., Miranda, M.R., Canepa, G.E., Alves, M.J., Pereira, C.A. Biochim. Biophys. Acta (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg