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TIMM44  -  translocase of inner mitochondrial...

Homo sapiens

Synonyms: MIMT44, Mitochondrial import inner membrane translocase subunit TIM44, TIM44
 
 
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Disease relevance of TIMM44

 

High impact information on TIMM44

  • ROS production, inflammatory responses, and cell proliferation in injured carotid artery were diminished by delivery of pcDNA3.1/TIM44 [2].
  • In the present work, we report the systematic screening of 14 candidate genes mapping to the region of linkage in affected TCO members, that led us to identify two novel variants respectively in exon 9 and exon 13 of TIMM44, a mitochondrial inner membrane translocase for the import in the mitochondria of nuclear-encoded proteins [1].

References

  1. Novel germline variants identified in the inner mitochondrial membrane transporter TIMM44 and their role in predisposition to oncocytic thyroid carcinomas. Bonora, E., Evangelisti, C., Bonichon, F., Tallini, G., Romeo, G. Br. J. Cancer (2006) [Pubmed]
  2. Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats. Matsuoka, T., Wada, J., Hashimoto, I., Zhang, Y., Eguchi, J., Ogawa, N., Shikata, K., Kanwar, Y.S., Makino, H. Diabetes (2005) [Pubmed]
 
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