The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

COLEC10  -  collectin sub-family member 10 (C-type...

Homo sapiens

Synonyms: CL-34, CL-L1, CLL1, Collectin liver protein 1, Collectin-10, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of COLEC10


High impact information on COLEC10

  • Expression cloning identified the antigen recognized as C-type lectin-like molecule-1 (CLL-1), a previously undescribed transmembrane glycoprotein [1].
  • CLL-1 expression was analyzed with a human anti-CLL-1 antibody that was generated from the single chain Fv fragment [1].
  • CLL-1 is absent on uncommitted CD34(+)/CD38(-) or CD34(+)/CD33(-) stem cells and present on subsets of CD34(+)/CD38(+) or CD34(+)/CD33(+) progenitor cells [1].
  • CLL-1 is restricted to the hematopoietic lineage, in particular to myeloid cells present in peripheral blood and bone marrow [1].
  • Elucidation of the role of two ancestor collectins of CL-K1 and CL-L1 could lead to see the biological function of collectin family [2].

Biological context of COLEC10

  • Abnormalities at 13q, though not correlated with particular clinical syndromes, are the subject of intense interest due to the possibility that one or more tumour suppressor genes relevant to the pathogenesis of CLL may be identified [3].


  1. C-type lectin-like molecule-1: a novel myeloid cell surface marker associated with acute myeloid leukemia. Bakker, A.B., van den Oudenrijn, S., Bakker, A.Q., Feller, N., van Meijer, M., Bia, J.A., Jongeneelen, M.A., Visser, T.J., Bijl, N., Geuijen, C.A., Marissen, W.E., Radosevic, K., Throsby, M., Schuurhuis, G.J., Ossenkoppele, G.J., de Kruif, J., Goudsmit, J., Kruisbeek, A.M. Cancer Res. (2004) [Pubmed]
  2. Identification and Characterization of a Novel Human Collectin CL-K1. Keshi, H., Sakamoto, T., Kawai, T., Ohtani, K., Katoh, T., Jang, S.J., Motomura, W., Yoshizaki, T., Fukuda, M., Koyama, S., Fukuzawa, J., Fukuoh, A., Yoshida, I., Suzuki, Y., Wakamiya, N. Microbiol. Immunol. (2006) [Pubmed]
  3. The search for genetic clues in chronic lymphocytic leukemia. Catovsky, D. Hematology and cell therapy. (1997) [Pubmed]
WikiGenes - Universities