The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Bai1  -  brain-specific angiogenesis inhibitor 1

Mus musculus

Synonyms: B830018M07Rik, Brain-specific angiogenesis inhibitor 1, R75078, mKIAA4089
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Bai1

  • The BAI1 expression decreased on the ischemic side after 24 h but BAP4 was not changed after the time-course of ischemia [1].
  • Because BAI1 possessed thrombospondin-type 1 repeats in its extracellular region, changes of BAI1 expression were examined in the focal cerebral ischemia model [1].
  • In this study, we investigated the in vivo antiangiogenic and antitumor effects of brain-specific angiogenesis inhibitor 1 (BAI1) using human glioblastoma cell lines [2].
 

High impact information on Bai1

 

Analytical, diagnostic and therapeutic context of Bai1

  • Northern and Western blot analyses demonstrated a unique pattern of BAI1 expression in the brain [1].
  • The ability of BAP4 to interact with BAI1 was confirmed by pulling-down BAI1 with GST-BAP4 protein and immunoprecipitation study using brain lysate [1].

References

  1. Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein. Koh, J.T., Lee, Z.H., Ahn, K.Y., Kim, J.K., Bae, C.S., Kim, H.H., Kee, H.J., Kim, K.K. Brain Res. Mol. Brain Res. (2001) [Pubmed]
  2. Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas. Kang, X., Xiao, X., Harata, M., Bai, Y., Nakazaki, Y., Soda, Y., Kurita, R., Tanaka, T., Komine, F., Izawa, K., Kunisaki, R., Setoyama, M., Nishimori, H., Natsume, A., Sunamura, M., Lozonshi, L., Saitoh, I., Tokino, T., Asano, S., Nakamura, Y., Tani, K. Cancer Gene Ther. (2006) [Pubmed]
 
WikiGenes - Universities