Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

UGT2A1 - UDP glucuronosyltransferase 2 family,...

Homo sapiens

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on UGT2A1

Based on the sequence homology, it has been designated hUGT2A1 [1].
Moreover, in situ hybrization staining reveals UGT2A1 mRNA expression in the olfactory sensory neuron nuclei [2].
Within the epithelium, UGT2A1 mRNA is mainly found in the sustentacular cells and to a lesser extent in Bowman's gland cells [2].
Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8 [3].
Exon-sharing is also seen with the 6-exon UGT2A1 and UGT2A2 genes [4].

Other interactions of UGT2A1

We report here three high-density maps of variations found among 48 Japanese individuals in three uridine diphosphate glycosyltransferase (UGT) genes, UGT2A1, UGT2B15, and UGT8 [3].

Analytical, diagnostic and therapeutic context of UGT2A1

In this work, we demonstrate the UGT2A1 mRNA expression in the olfactory bulb, using in situ hybridization and quantitative reverse transcription-polymerase chain reaction (RT-PCR) techniques [2].

References

Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase. Jedlitschky, G., Cassidy, A.J., Sales, M., Pratt, N., Burchell, B. Biochem. J. (1999) [Pubmed]
Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis. Heydel, J., Leclerc, S., Bernard, P., Pelczar, H., Gradinaru, D., Magdalou, J., Minn, A., Artur, Y., Goudonnet, H. Brain Res. Mol. Brain Res. (2001) [Pubmed]
Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. Iida, A., Saito, S., Sekine, A., Mishima, C., Kitamura, Y., Kondo, K., Harigae, S., Osawa, S., Nakamura, Y. J. Hum. Genet. (2002) [Pubmed]
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Mackenzie, P.I., Walter Bock, K., Burchell, B., Guillemette, C., Ikushiro, S., Iyanagi, T., Miners, J.O., Owens, I.S., Nebert, D.W. Pharmacogenet. Genomics (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

Ugt2a1	Mus musculus
Ugt2a1	Rattus norvegicus

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.