Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Cplx2 - complexin 2

Rattus norvegicus

Synonyms: CPX II, Complexin II, Complexin-2, Synaphin-1

Hill, J.J. et al., Tokumaru, H. et al.

Hill, Callaghan, Ding, Kelly, Chakravarthy,

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High impact information on Cplx2

SNARE complex oligomerization by synaphin/complexin is essential for synaptic vesicle exocytosis [1].
This is the first report of a phosphorylation site on complexin 2 [2].
Most interestingly, we have found that complexin 2, an important regulator of neurotransmitter release and synaptic plasticity, is phosphorylated at serine 93 upon OA treatment of neurons [2].

References

SNARE complex oligomerization by synaphin/complexin is essential for synaptic vesicle exocytosis. Tokumaru, H., Umayahara, K., Pellegrini, L.L., Ishizuka, T., Saisu, H., Betz, H., Augustine, G.J., Abe, T. Cell (2001) [Pubmed]
Identification of okadaic acid-induced phosphorylation events by a mass spectrometry approach. Hill, J.J., Callaghan, D.A., Ding, W., Kelly, J.F., Chakravarthy, B.R. Biochem. Biophys. Res. Commun. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CPLX2	Bos taurus
CPLX2	Canis lupus familiaris
cplx2	Danio rerio
LOC100857281	Gallus gallus
CPLX2	Homo sapiens
CPLX2	Macaca mulatta
Cplx2	Mus musculus
LOC750228	Pan troglodytes
cplx2	Xenopus (Silurana) tropicalis

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