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Gene Review

mlpH  -  MlpH

Borrelia burgdorferi B31

 
 
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Disease relevance of mlpH

  • Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family [1].
 

High impact information on mlpH

  • A DNA microarray containing fragments of 137 Borrelia burgdorferi B31 putative lipoprotein genes was used to examine Lyme disease spirochetes [2].
  • Further screenings of B. burgdorferi 297 genomic libraries led to the identification of three additional 2.9 lipoprotein genes, renamed herein mlp, for multicopy lipoprotein genes [1].
  • We previously reported on the existence of a family of lipoprotein genes, designated 2.9 lipoprotein genes, encoded in at least seven versions on the circular (supercoiled) cp32 and cp18 plasmids of Borrelia burgdorferi 297 [1].
 

Analytical, diagnostic and therapeutic context of mlpH

References

  1. Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Yang, X., Popova, T.G., Hagman, K.E., Wikel, S.K., Schoeler, G.B., Caimano, M.J., Radolf, J.D., Norgard, M.V. Infect. Immun. (1999) [Pubmed]
  2. DNA microarray assessment of putative Borrelia burgdorferi lipoprotein genes. Liang, F.T., Nelson, F.K., Fikrig, E. Infect. Immun. (2002) [Pubmed]
 
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