The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

popA  -  POPA protein

Ralstonia solanacearum GMI1000

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of popA

  • To that aim we created transgenic tobacco plants in which the pathogen-inducible promoter of the hsr203J gene from tobacco controls the expression of the popA elicitor gene from Ralstonia solanacearum [1].
 

High impact information on popA

  • These two proteins induced the same pattern of response on Petunia, as a function of the genotypes tested. popA, the structural gene for PopA1, maps outside of the hrp gene cluster but belongs to the hrp regulon [2].
  • A popA mutant remained fully pathogenic on sensitive plants, indicating that this gene is not essential for pathogenicity [2].
  • In order to investigate the role of the different proteins encoded by the hrp gene cluster of the phytopathogenic bacterium Ralstonia solanacearum, non-polar mutants in all hrp genes (except for hrcQ) were analysed for their interactions with plants, their ability to secrete the PopA protein and their production of the Hrp pilus [3].
  • Two of these proteins, PopB and PopC, are encoded by genes located downstream of popA and constitute an operon with popA. popABC mutants retain the wild-type ability to cause disease in hosts and to elicit the hypersensitive response on non-hosts [4].
  • An hrpY mutant is defective in pilus production, impaired in interactions with plants and in secretion of the PopA protein but not in attachment to plant cells [5].
 

Other interactions of popA

  • Moreover, we show that this specific plant cell induction of hrp genes is controlled by a gene, called prhA (plant regulator of hrp genes), located next to popA [6].

References

  1. A local accumulation of the Ralstonia solanacearum PopA protein in transgenic tobacco renders a compatible plant-pathogen interaction incompatible. Belbahri, L., Boucher, C., Candresse, T., Nicole, M., Ricci, P., Keller, H. Plant J. (2001) [Pubmed]
  2. PopA1, a protein which induces a hypersensitivity-like response on specific Petunia genotypes, is secreted via the Hrp pathway of Pseudomonas solanacearum. Arlat, M., Van Gijsegem, F., Huet, J.C., Pernollet, J.C., Boucher, C.A. EMBO J. (1994) [Pubmed]
  3. Genetic dissection of Ralstonia solanacearum hrp gene cluster reveals that the HrpV and HrpX proteins are required for Hrp pilus assembly. Van Gijsegem, F., Vasse, J., De Rycke, R., Castello, P., Boucher, C. Mol. Microbiol. (2002) [Pubmed]
  4. Two novel proteins, PopB, which has functional nuclear localization signals, and PopC, which has a large leucine-rich repeat domain, are secreted through the hrp-secretion apparatus of Ralstonia solanacearum. Guéneron, M., Timmers, A.C., Boucher, C., Arlat, M. Mol. Microbiol. (2000) [Pubmed]
  5. Ralstonia solanacearum produces hrp-dependent pili that are required for PopA secretion but not for attachment of bacteria to plant cells. Van Gijsegem, F., Vasse, J., Camus, J.C., Marenda, M., Boucher, C. Mol. Microbiol. (2000) [Pubmed]
  6. PrhA controls a novel regulatory pathway required for the specific induction of Ralstonia solanacearum hrp genes in the presence of plant cells. Marenda, M., Brito, B., Callard, D., Genin, S., Barberis, P., Boucher, C., Arlat, M. Mol. Microbiol. (1998) [Pubmed]
 
WikiGenes - Universities