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Gene Review:

flgI - flagellar basal body P-ring protein FlgI

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Khambaty, F.M. et al., Winstanley, C. et al.

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Disease relevance of flgI

Molecular genetics of the flgI region and its role in flagellum biosynthesis in Caulobacter crescentus [1].
DNA and deduced protein sequences suggested the presence on this fragment of two complete genes homologous to flgH and flgI from Salmonella typhimurium [2].

High impact information on flgI

In this study, a clone containing the 5.3-kb flaP region was shown to contain the flgI, cheL, and flbY genes arranged in an operon with transcription proceeding from flgI to flbY [1].
Therefore, the flgI-encoded P-ring protein is required for normal flagellin and hook protein synthesis, suggesting that basal body assembly may play a role in the regulation of flagellar gene expression [1].

References

Molecular genetics of the flgI region and its role in flagellum biosynthesis in Caulobacter crescentus. Khambaty, F.M., Ely, B. J. Bacteriol. (1992) [Pubmed]
Molecular cloning of two Pseudomonas flagellin genes and basal body structural genes. Winstanley, C., Morgan, J.A., Pickup, R.W., Saunders, J.R. Microbiology (Reading, Engl.) (1994) [Pubmed]

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