The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

recB  -  exonuclease V subunit beta

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of recB

 

High impact information on recB

  • Such mutations also restore SOS induction in quinolone-treated gyr+ recB- strains [3].
  • (c) Both recA and recB mutations eliminate inversion formation [4].
  • We have investigated the genetic organization of the recB (exonuclease V) and recC (exonuclease V) genes of Salmonella typhimurium [2].
  • In contrast to their severe defects in recombination, DNA repair and plasmid maintenance, recB recJ mutants of S. typhimurium behave similarly to the wild type in the segregation of chromosome duplications [5].
  • recB recJ mutants of Salmonella typhimurium are deficient in transduction of chromosomal markers and ColE1-derived plasmids, and also in the maintenance of ColE1 and F plasmids [5].
 

Biological context of recB

  • A detailed genetic map is constructed that includes the relative order in the chromosome, P22 cotransduction frequencies, and the orientation of transcription of the recB and recC genes [2].

References

  1. Lethal transposition of Mud phages in Rec- strains of Salmonella typhimurium. Sonti, R.V., Keating, D.H., Roth, J.R. Genetics (1993) [Pubmed]
  2. recB and recC genes of Salmonella typhimurium. Mahan, M.J., Roth, J.R. J. Bacteriol. (1989) [Pubmed]
  3. A class of gyrase mutants of Salmonella typhimurium show quinolone-like lethality and require rec functions for viability. Garí, E., Figueroa-Bossi, N., Blanc-Potard, A.B., Spirito, F., Schmid, M.B., Bossi, L. Mol. Microbiol. (1996) [Pubmed]
  4. Approaches to half-tetrad analysis in bacteria: recombination between repeated, inverse-order chromosomal sequences. Segall, A.M., Roth, J.R. Genetics (1994) [Pubmed]
  5. recB recJ mutants of Salmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance. Garzón, A., Beuzón, C.R., Mahan, M.J., Casadesús, J. Mol. Gen. Genet. (1996) [Pubmed]
 
WikiGenes - Universities