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Gene Review

cebpa  -  CCAAT/enhancer binding protein (C/EBP), alpha

Danio rerio

Synonyms: SO:0000704, c/ebpa, cb1062, wu:fj20f03
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High impact information on cebpa

  • CONCLUSION: Expression of the truncated isoforms of cebpa alters the developmental pattern of hematopoietic progenitor cells during embryogenesis [1].
  • A deletion mutation of cebpa (zD420), which mimics the human dominant-negative mutations of C/EBPalpha, was transfected into CV1 cell line to evaluate its transcriptional activity in vitro and injected into zebrafish embryos at the one- to two-cell stage to examine its effects on primitive hematopoiesis during early zebrafish development [1].

Analytical, diagnostic and therapeutic context of cebpa


  1. Dominant-interfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish. Liu, T.X., Rhodes, J., Deng, M., Hsu, K., Radomska, H.S., Kanki, J.P., Tenen, D.G., Look, A.T. Exp. Hematol. (2007) [Pubmed]
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