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Gene Review:

MPP7 - membrane protein, palmitoylated 7 (MAGUK...

Homo sapiens

Synonyms: FLJ32798, MAGUK p55 subfamily member 7

Katoh, M. et al., Bohl, J. et al.

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Disease relevance of MPP7

Human MPP7 mRNA was expressed in placenta, brain, testis as well as in uterus tumor, bladder tumor, and lymphoma [1].
Microsatellite marker D10S588, linked to IDDM and hereditary thrombocytopenia, was located within the MPP7 gene at human chromosome 10p12 [1].

High impact information on MPP7

The tripartite complex forms in a ratio of 1:1:1 and localizes to epithelial adherens junctions in a manner dependent upon MPP7 [2].
Here, we identified and characterized a novel member of MPP gene family, MPP7, by using bioinformatics [1].
Uncharacterized FLJ32798 cDNAs (BC038105 and AK057360) were derived from human MPP7 gene [1].

References

Identification and characterization of human MPP7 gene and mouse Mpp7 gene in silico. Katoh, M., Katoh, M. Int. J. Mol. Med. (2004) [Pubmed]
The Stardust Family Protein MPP7 Forms a Tripartite Complex with LIN7 and DLG1 That Regulates the Stability and Localization of DLG1 to Cell Junctions. Bohl, J., Brimer, N., Lyons, C., Vande Pol, S.B. J. Biol. Chem. (2007) [Pubmed]

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AgaP_AGAP010230	Anopheles gambiae str. PEST
MPP7	Bos taurus
magu-1	Caenorhabditis elegans
MPP7	Canis lupus familiaris
mpp7	Danio rerio
metro	Drosophila melanogaster
MPP7	Gallus gallus
MPP7	Macaca mulatta
Mpp7	Mus musculus
MPP7	Pan troglodytes
Mpp7	Rattus norvegicus
mpp7	Xenopus (Silurana) tropicalis

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