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Gene Review

STP-A11  -  saimiri transformation-associated protein

Saimiriine herpesvirus 2

 
 
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Disease relevance of STP-A11

 

High impact information on STP-A11

 

Associations of STP-A11 with chemical compounds

  • Mutational analysis of STP-A11 showed that binding to src kinase required the tyrosine residue at 115, showing that YAEV/I is a likely binding motif for src [5].

References

  1. Primary structure of the herpesvirus saimiri genome. Albrecht, J.C., Nicholas, J., Biller, D., Cameron, K.R., Biesinger, B., Newman, C., Wittmann, S., Craxton, M.A., Coleman, H., Fleckenstein, B. J. Virol. (1992) [Pubmed]
  2. Herpesvirus saimiri-encoded proteins Tip and StpC modulate human immunodeficiency virus type 1 replication in T-cell lines and lymphocytes independently of viral tropism. Raymond, A.D., Hasham, M.G., Tsygankov, A.Y., Henderson, E.E. Virology (2004) [Pubmed]
  3. Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions. Raymond, A.D., Hasham, M., Tsygankov, A.Y., Henderson, E.E. Curr. HIV Res. (2007) [Pubmed]
  4. Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiri. Jung, J.U., Trimble, J.J., King, N.W., Biesinger, B., Fleckenstein, B.W., Desrosiers, R.C. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  5. Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular src. Lee, H., Trimble, J.J., Yoon, D.W., Regier, D., Desrosiers, R.C., Jung, J.U. J. Virol. (1997) [Pubmed]
 
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