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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CTRB1  -  chymotrypsinogen B1

Homo sapiens

Synonyms: CTRB, Chymotrypsinogen B
 
 
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High impact information on CTRB1

  • Loss of heterozygosity on chromosome 16 was detected in 36 (52%) of 69 informative cases, and the common region of allele loss in these 36 tumors was located between the HP locus (16q22.1) and the CTRB locus (16q22.3-q23.2) [1].
  • Tyrosine aminotransferase and chymotrypsinogen B are linked to haptoglobin on human chromosome 16q: comparison of genetic and physical distances [2].
  • For CTRB, two TaqI RFLPs with a polymorphism information content of 0.60 derived from haplotype frequencies are described [2].
  • Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation [3].
 

Analytical, diagnostic and therapeutic context of CTRB1

References

  1. Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. Tsuda, H., Zhang, W.D., Shimosato, Y., Yokota, J., Terada, M., Sugimura, T., Miyamura, T., Hirohashi, S. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  2. Tyrosine aminotransferase and chymotrypsinogen B are linked to haptoglobin on human chromosome 16q: comparison of genetic and physical distances. Westphal, E.M., Burmeister, M., Wienker, T.F., Lehrach, H., Bender, K., Scherer, G. Genomics (1987) [Pubmed]
  3. Human chymotrypsinogen B production with Pichia pastoris by integrated development of fermentation and downstream processing. Part 1. Fermentation. Curvers, S., Brixius, P., Klauser, T., Thömmes, J., Weuster-Botz, D., Takors, R., Wandrey, C. Biotechnol. Prog. (2001) [Pubmed]
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