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Gene Review

Mycl  -  v-myc myelocytomatosis viral oncogene...

Mus musculus

Synonyms: AW536278, L-myc, Lmyc-1, Lmyc1, Mycl1, ...
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Disease relevance of Mycl1


High impact information on Mycl1

  • Inhibition of protein synthesis by cycloheximide for 4 h induced a 70% increase in Lmyc and 30% increase in Bmyc transcript levels, indicating that the expression of these genes is negatively regulated by a short-lived protein [1].
  • We assigned the mouse CBF-C gene (designated Nfyc) to chromosome 4 with tight linkage to Lmyc [2].
  • Mapping of Lmyc and Nmyc to rat chromosomes 5 and 6 [3].

Anatomical context of Mycl1


  1. Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells. Ingvarsson, S., Sundaresan, S., Jin, P., Francke, U., Asker, C., Sümegi, J., Klein, G., Sejersen, T. Oncogene (1988) [Pubmed]
  2. Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. Sinha, S., Maity, S.N., Seldin, M.F., de Crombrugghe, B. Genomics (1996) [Pubmed]
  3. Mapping of Lmyc and Nmyc to rat chromosomes 5 and 6. Ingvarsson, S., Asker, C., Wirschubsky, Z., Szpirer, J., Levan, G., Klein, G., Sümegi, J. Somat. Cell Mol. Genet. (1987) [Pubmed]
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