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Gene Review:

F09G2.3 - Protein F09G2.3

Caenorhabditis elegans

Heider, U. et al., Orchard, S.S. et al.

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Disease relevance of permease

Identification and functional characterization of a Xenorhabdus nematophila oligopeptide permease [1].
Differential display of genes expressed in the filarial nematode Litomosoides sigmodontis reveals a putative phosphate permease up-regulated after depletion of Wolbachia endobacteria [2].

High impact information on permease

Peptide-feeding studies indicated that this opp operon encodes a functional oligopeptide permease [1].
In Caenorhabditis elegans, the knockdown of a homologous phosphate permease results in embryonic lethality, with the production of degenerating embryos, a phenotype also seen in filarial nematodes after depletion of Wolbachia with tetracycline [2].

References

Identification and functional characterization of a Xenorhabdus nematophila oligopeptide permease. Orchard, S.S., Goodrich-Blair, H. Appl. Environ. Microbiol. (2004) [Pubmed]
Differential display of genes expressed in the filarial nematode Litomosoides sigmodontis reveals a putative phosphate permease up-regulated after depletion of Wolbachia endobacteria. Heider, U., Blaxter, M., Hoerauf, A., Pfarr, K.M. Int. J. Med. Microbiol. (2006) [Pubmed]

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SLC20A2	Bos taurus
B0222.2	Caenorhabditis elegans
B0222.3	Caenorhabditis elegans
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NCU09564	Neurospora crassa OR74A
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PHO89	Saccharomyces cerevisiae S288c
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