Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Usp22 - ubiquitin specific peptidase 22

Mus musculus

Synonyms: AI427806, Deubiquitinating enzyme 22, Kiaa1063, Ubiquitin carboxyl-terminal hydrolase 22, Ubiquitin thioesterase 22, ...

Lee, H.J. et al.

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High impact information on Usp22

5. Embryos at E12.5 showed the pronounced expression of Usp22 during the early embryonic development, although its expression was not detectable in the gut, liver and heart [1].
5. Whole mount in situ hybridization staining revealed that Usp22 was expressed in the midbrain, forebrain, hindbrain and dorsal root ganglia of embryos at E12 [1].

Analytical, diagnostic and therapeutic context of Usp22

We investigated the expression level of Usp22 mRNA and the localization during implantation and early pregnancy by in situ hybridization [1].
Interestingly, Northern blot analysis showed the strong expression of Usp22 between embryonic days E10.5 and E12 [1].

References

The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Lee, H.J., Kim, M.S., Shin, J.M., Park, T.J., Chung, H.M., Baek, K.H. Gene Expr. Patterns (2006) [Pubmed]

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AgaP_AGAP012119	Anopheles gambiae str. PEST
AGOS_AFR551W	Ashbya gossypii ATCC 10895
USP22	Bos taurus
USP22	Canis lupus familiaris
usp22	Danio rerio
not	Drosophila melanogaster
USP22	Gallus gallus
USP22	Homo sapiens
KLLA0C06974g	Kluyveromyces lactis NRRL Y-1140
MGG_03527	Magnaporthe oryzae 70-15
NCU02375	Neurospora crassa OR74A
Os04g0647300	Oryza sativa Japonica Group
USP22	Pan troglodytes
Usp22	Rattus norvegicus
UBP8	Saccharomyces cerevisiae S288c
ubp8	Schizosaccharomyces pombe 972h-
usp22	Xenopus (Silurana) tropicalis

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