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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Ganglia

 
 
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Disease relevance of Ganglia

 

Psychiatry related information on Ganglia

 

High impact information on Ganglia

  • Here we show that Cited2-/- embryos die with cardiac malformations, adrenal agenesis, abnormal cranial ganglia and exencephaly [10].
  • Here we report that mice homozygous for a targeted null mutation at the CrkL locus (gene symbol Crkol for mice) exhibit defects in multiple cranial and cardiac neural crest derivatives including the cranial ganglia, aortic arch arteries, cardiac outflow tract, thymus, parathyroid glands and craniofacial structures [11].
  • We describe cloning of a candidate dt gene, dystonin, that is predominantly expressed in the dorsal root ganglia and other sites of neurodegeneration in dt mice [12].
  • The brain and spinal cord of the mutants appear normal, but their olfactory epithelium and sympathetic, parasympathetic, and enteric ganglia are severely affected [13].
  • Cleavage of NgR and other GPI-linked proteins from the cell surface renders axons of dorsal root ganglia insensitive to OMgp [14].
 

Chemical compound and disease context of Ganglia

 

Biological context of Ganglia

 

Anatomical context of Ganglia

 

Associations of Ganglia with chemical compounds

  • Synthesis of substance P is reduced by some 90% in ganglia from rats treated neonatally with capsaicin, a drug which is thought to destroy a population of primary afferent neurones [30].
  • These receptors do not bind alpha-bungarotoxin but have a high affinity for nicotine and antibodies raised against them block the function of acetylcholine receptors in ciliary ganglia [31].
  • We report here that E/C8-positive mesenchymal cells of the arches can develop into neurones spontaneously in culture, or can migrate into aneural guts with which they are co-cultured and form enteric ganglia [32].
  • At a dose of 1.8 to 10 nanomoles, the peptide enhanced and prolonged the postganglionic discharge elicited by acetyl-beta-methylcholine, enhanced muscarinic transmission in ganglia treated with an anticholinesterase agent, and enhanced the late muscarinic discharge elicited by acetylcholine [33].
  • Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops [34].
 

Gene context of Ganglia

 

Analytical, diagnostic and therapeutic context of Ganglia

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