The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

SF3B3  -  splicing factor 3b, subunit 3, 130kDa

Homo sapiens

Synonyms: KIAA0017, Pre-mRNA-splicing factor SF3b 130 kDa subunit, RSE1, SAP 130, SAP130, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on SF3B3

  • We have identified a 130 kDa subunit of TFTC (SAP130) that shares homology with the large subunit of UV-damaged DNA-binding factor [1].
  • RESULTS: Increased SF 3-B-3 concentrations and 3-B-3/GAG ratio were found in OA, compared with RA or normal knees, with higher 3-B-3 and 3-B-3/GAG in LJOA and NGOA than in CPA [2].
 

Biological context of SF3B3

  • In the second example, beta-propeller domains were predicted in the large subunit of UV-damaged DNA-binding protein and in related proteins, including the large subunit of cleavage-polyadenylation specificity factor, the yeast Rse1p and human SAP130 pre-mRNA splicing factors and the fission yeast Rik1p gene silencing protein [3].
 

Anatomical context of SF3B3

References

  1. UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. Brand, M., Moggs, J.G., Oulad-Abdelghani, M., Lejeune, F., Dilworth, F.J., Stevenin, J., Almouzni, G., Tora, L. EMBO J. (2001) [Pubmed]
  2. Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in arthritic and normal knees. Belcher, C., Yaqub, R., Fawthrop, F., Bayliss, M., Doherty, M. Ann. Rheum. Dis. (1997) [Pubmed]
  3. PSI-BLAST searches using hidden markov models of structural repeats: prediction of an unusual sliding DNA clamp and of beta-propellers in UV-damaged DNA-binding protein. Neuwald, A.F., Poleksic, A. Nucleic Acids Res. (2000) [Pubmed]
  4. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Martinez, E., Palhan, V.B., Tjernberg, A., Lymar, E.S., Gamper, A.M., Kundu, T.K., Chait, B.T., Roeder, R.G. Mol. Cell. Biol. (2001) [Pubmed]
 
WikiGenes - Universities