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Gene Review

Coro1c  -  coronin, actin binding protein 1C

Mus musculus

Synonyms: AL022675, AW455561, AW548837, Coronin-1C, Coronin-3, ...
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High impact information on Coro1c

  • Cytosolic coronin 3 showed a high degree of phosphorylation, which is likely to regulate the subcellular localization of the protein [1].
  • Coronin 3 is exclusively extracted as an oligomer from both the cytosol and the membrane fraction [1].
  • Our results favour a role for coronin 3 in neuron morphogenesis and possibly migration [2].
  • All murine brain areas express coronin 3 during embryogenesis and the first postnatal stages [2].
  • Full-length coronin 3 among other areas localized to outgrowing neurites, whereas truncated proteins efficiently suppressed neurite formation [2].

Anatomical context of Coro1c


  1. Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus. Spoerl, Z., Stumpf, M., Noegel, A.A., Hasse, A. J. Biol. Chem. (2002) [Pubmed]
  2. Coronin 3 and its role in murine brain morphogenesis. Hasse, A., Rosentreter, A., Spoerl, Z., Stumpf, M., Noegel, A.A., Clemen, C.S. Eur. J. Neurosci. (2005) [Pubmed]
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