High impact information on Coro1c

• Cytosolic coronin 3 showed a high degree of phosphorylation, which is likely to regulate the subcellular localization of the protein [1].
• Coronin 3 is exclusively extracted as an oligomer from both the cytosol and the membrane fraction [1].
• Our results favour a role for coronin 3 in neuron morphogenesis and possibly migration [2].
• All murine brain areas express coronin 3 during embryogenesis and the first postnatal stages [2].
• Full-length coronin 3 among other areas localized to outgrowing neurites, whereas truncated proteins efficiently suppressed neurite formation [2].

Anatomical context of Coro1c

• Consistently, coronin 3 is abundant in differentiating neuro-2a and PC-12 cells and in primary oligodendrocytes [2].

References