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Gene Review

shk1  -  PAK-related kinase Shk1

Schizosaccharomyces pombe 972h-

 
 
 
 
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High impact information on pak1

  • Gene disruption of pak1+ establishes that, like cdc42+, pak1+ function is required for cell viability [1].
  • The pak1+ gene encodes a 72 kDa protein containing a putative p21-binding domain near its amino-terminus and a serine/threonine kinase domain near its carboxyl-terminus [1].

References

  1. Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating. Ottilie, S., Miller, P.J., Johnson, D.I., Creasy, C.L., Sells, M.A., Bagrodia, S., Forsburg, S.L., Chernoff, J. EMBO J. (1995) [Pubmed]
 
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