Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

hba1 - Ran GTPase binding protein Hba1

Schizosaccharomyces pombe 972h-

Benko, Z. et al., Turi, T.G. et al.

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High impact information on hba1

The characterization of hba1 thus demonstrates a novel mechanism of drug resistance in S. pombe [1].
We previously identified four nuclear genes (caf1+-caf4+) in Schizosaccharomyces pombe, mutations in which confer resistance to caffeine and brefeldin A. caf1+, caf2+ and caf4+ were sequenced and found to be identical to the multidrug-resistance/stress-response genes hba1, crm1 and trr1, respectively [2].

References

Characterization of a nuclear protein conferring brefeldin A resistance in Schizosaccharomyces pombe. Turi, T.G., Mueller, U.W., Sazer, S., Rose, J.K. J. Biol. Chem. (1996) [Pubmed]
The transcription factor Pap1/Caf3 plays a central role in the determination of caffeine resistance in Schizosaccharomyces pombe. Benko, Z., Fenyvesvolgyi, C., Pesti, M., Sipiczki, M. Mol. Genet. Genomics (2004) [Pubmed]

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