Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

sim1a - single-minded family bHLH transcription...

Danio rerio

Synonyms: SO:0000704, Single-minded homolog 1-A, sim1

Eaton, J.L. et al., Serluca, F.C. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of sim1

We have defined regions of the intermediate mesoderm as candidates for the pronephric field by expression patterns of the Wilms' Tumor suppressor gene (wt1), single-minded 1 (sim1) and pax2 [1].

High impact information on sim1

1. The most posterior cells contribute to the nephric duct, and these express pax2.1 and sim1, but not wt1 [1].
The zebrafish bHLH PAS transcriptional regulator, single-minded 1 (sim1), is required for isotocin cell development [2].
Here we show that sim1 is expressed in the zebrafish forebrain and is required for isotocin cell development [2].

Anatomical context of sim1

The expression pattern of sim1 mRNA in the embryonic forebrain is dynamic and complex, and overlaps with isotocin expression in the preoptic area [2].

References

Pre-pattern in the pronephric kidney field of zebrafish. Serluca, F.C., Fishman, M.C. Development (2001) [Pubmed]
The zebrafish bHLH PAS transcriptional regulator, single-minded 1 (sim1), is required for isotocin cell development. Eaton, J.L., Glasgow, E. Dev. Dyn. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

SIM1	Bos taurus
SIM1	Canis lupus familiaris
SIM1	Gallus gallus
SIM1	Homo sapiens
SIM1	Macaca mulatta
Sim1	Mus musculus
SIM1	Pan troglodytes
Sim1	Rattus norvegicus
sim1	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.