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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SCARB1  -  scavenger receptor class B, member 1

Bos taurus

 
 
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High impact information on SCARB1

  • This occurs by either endocytosis, which has been described for very low density lipoprotein receptors (VLDLr), for LDL receptors (LDLr), and by the selective uptake pathway described for the scavenger receptor class B type 1 receptor (SRB1) and the recently described ovarian receptor, lipoprotein receptor-related protein 8 (LRP8) [1].
  • Advanced glycation end products (AGE) are known to serve as ligands for the scavenger receptors such as SR-A, CD36 and SR-BI [2].
  • Sequence of the bovine HDL-receptor (SR-BI) cDNA and changes in receptor mRNA expression during granulosa cell luteinization in vivo and in vitro [3].
  • In this study, we have sequenced the bovine SR-BI HDL-receptor and examined changes in expression of the receptor mRNA during corpus luteum development in vivo and granulosa cell luteinization in vitro [3].

References

  1. Lipid transport in the developing bovine follicle: messenger RNA expression increases for selective uptake receptors and decreases for endocytosis receptors. Argov, N., Moallem, U., Sklan, D. Biol. Reprod. (2004) [Pubmed]
  2. Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) serves as an endothelial receptor for advanced glycation end products (AGE). Jono, T., Miyazaki, A., Nagai, R., Sawamura, T., Kitamura, T., Horiuchi, S. FEBS Lett. (2002) [Pubmed]
  3. Sequence of the bovine HDL-receptor (SR-BI) cDNA and changes in receptor mRNA expression during granulosa cell luteinization in vivo and in vitro. Rajapaksha, W.R., McBride, M., Robertson, L., O'Shaughnessy, P.J. Mol. Cell. Endocrinol. (1997) [Pubmed]
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