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Gene Review

tfdK  -  ORF24

Ralstonia eutropha JMP134

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Disease relevance of tfdK


High impact information on tfdK


Biological context of tfdK

  • We identified an open reading frame on plasmid pJP4, which was designated tfdK, whose translation product TfdK was highly hydrophobic and showed resemblance to transport proteins of the major facilitator superfamily [1].


  1. The tfdK gene product facilitates uptake of 2,4-dichlorophenoxyacetate by Ralstonia eutropha JMP134(pJP4). Leveau, J.H., Zehnder, A.J., van der Meer, J.R. J. Bacteriol. (1998) [Pubmed]
  2. Dynamics of multigene expression during catabolic adaptation of Ralstonia eutropha JMP134 (pJP4) to the herbicide 2, 4-dichlorophenoxyacetate. Leveau, J.H., König, F., Füchslin, H., Werlen, C., Van Der Meer, J.R. Mol. Microbiol. (1999) [Pubmed]
  3. Novel 2,4-dichlorophenoxyacetic acid degradation genes from oligotrophic Bradyrhizobium sp. strain HW13 isolated from a pristine environment. Kitagawa, W., Takami, S., Miyauchi, K., Masai, E., Kamagata, Y., Tiedje, J.M., Fukuda, M. J. Bacteriol. (2002) [Pubmed]
  4. Characterization of a second tfd gene cluster for chlorophenol and chlorocatechol metabolism on plasmid pJP4 in Ralstonia eutropha JMP134(pJP4). Laemmli, C.M., Leveau, J.H., Zehnder, A.J., van der Meer, J.R. J. Bacteriol. (2000) [Pubmed]
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