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Gene Review

STON1-GTF2A1L  -  STON1-GTF2A1L readthrough

Homo sapiens

Synonyms: SALF
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Disease relevance of SALF

  • These patients were further subclassified depending upon the interval between the onset of jaundice and the onset of encephalopathy into hyperacute (HALF; interval 0-7 days), acute (ALF; interval 8-28 days) and subacute liver failure (SALF; interval 4-12 weeks) [1].

High impact information on SALF

  • In addition, a rare ALF-containing cDNA, which possesses an extended N terminus (Stoned B/TFIIAalpha/beta-like factor; SALF) has also been identified [2].
  • Management included ambulation as desired, regular hospital diet without salf restriction, blood pressure measured 4 times daily, weight and urine protein determined 3 times each week, creatinine clearance determined weekly, and serial sonography to monitor fetal growth [3].

Analytical, diagnostic and therapeutic context of SALF

  • The inhibitory factor was purified by salf fractionation and gel chromatography and the effect found to be associated with alpha-globulins of high lipid content which are probably alpha-lipoproteins [4].


  1. Prognostic evaluation of early indicators in fulminant hepatic failure by multivariate analysis. Dhiman, R.K., Seth, A.K., Jain, S., Chawla, Y.K., Dilawari, J.B. Dig. Dis. Sci. (1998) [Pubmed]
  2. Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testis. Upadhyaya, A.B., Lee, S.H., DeJong, J. J. Biol. Chem. (1999) [Pubmed]
  3. Management of pregnancy-induced hypertension in the nullipara. Hauth, J.C., Cunningham, F.G., Whalley, P.J. Obstetrics and gynecology. (1976) [Pubmed]
  4. Identification of an immunosuppressive factor in pregnancy serum. Stimson, W.H., Blackstock, J.C. Obstetrics and gynecology. (1976) [Pubmed]
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