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Gene Review

ald1  -  aldehyde dehydrogenase

Acinetobacter sp. ADP1

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Disease relevance of ald1

  • The ald1 gene was disrupted by homologous recombination on the Acinetobacter genome [1].
  • The ald1 gene was stably expressed in Escherichia coli, and the gene product (recombinant Ald1 [rAld1]) was purified to apparent homogeneity by gel electrophoresis. rAld1 showed enzyme activity toward n-alkanals (C(4) to C(14)), with a preference for longer carbon chains within the tested range; the highest activity was obtained with tetradecanal [1].

High impact information on ald1


  1. Long-chain aldehyde dehydrogenase that participates in n-alkane utilization and wax ester synthesis in Acinetobacter sp. strain M-1. Ishige, T., Tani, A., Sakai, Y., Kato, N. Appl. Environ. Microbiol. (2000) [Pubmed]
  2. Long-chain alcohol and aldehyde dehydrogenase activities in Acinetobacter calcoaceticus strain HO1-N. Fox, M.G., Dickinson, F.M., Ratledge, C. J. Gen. Microbiol. (1992) [Pubmed]
  3. Ultracytochemical localization of aldehyde dehydrogenase in Acinetobacter calcoaceticus. Sorger, H., Aurich, H., Fricke, B., Vorisek, J. J. Basic Microbiol. (1986) [Pubmed]
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