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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

salE  -  salicylate esterase

Acinetobacter sp. ADP1

 
 
 
 
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High impact information on salE

  • SalR appeared to regulate expression of salA but not salE [1].
  • Studies of mutants with disruptions of genes of the beta-ketoadipate pathway with or without an additional salE mutation confirmed that ethyl salicylate and salicylate were channeled into the beta-ketoadipate pathway at the level of catechol and thence dissimilated by the cat gene products [1].
  • A mutant of ADP1 with a Km(r) cassette introduced into salE had lost the ability to utilize only ethyl and methyl salicylates of the esters tested as sole carbon sources, and no esterase activity against ethyl salicylate could be detected in cell extracts [1].

References

  1. sal genes determining the catabolism of salicylate esters are part of a supraoperonic cluster of catabolic genes in Acinetobacter sp. strain ADP1. Jones, R.M., Pagmantidis, V., Williams, P.A. J. Bacteriol. (2000) [Pubmed]
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