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Gene Review:

SLC43A3 - solute carrier family 43, member 3

Homo sapiens

Synonyms: DKFZp762A227, EEG1, Eeg1, FOAP-13, PRO1659, ...

Stuart, R.O. et al., Clemens, B. et al.

Stuart, Pavlova, Beier, Li, Krijanovski, Nigam,

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High impact information on SLC43A3

The EEG1 gene is composed of 14 exons spanning a 20-kb region at human chromosome 11p12 and the syntenic region of mouse chromosome 2 [1].
POV-1 and EEG1, like glucose transporters, displayed very early maximal gene expression [1].
EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis [1].
Six EEG1 exons have previously been assigned to a longer isoform of eosinophil major basic protein termed proteoglycan 2 [1].

Analytical, diagnostic and therapeutic context of SLC43A3

Baseline waking EEG (EEG1) was recorded in the untreated state, the second EEG (EEG2) was done after 8 weeks of reaching the therapeutic dose [2].

References

EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis. Stuart, R.O., Pavlova, A., Beier, D., Li, Z., Krijanovski, Y., Nigam, S.K. Am. J. Physiol. Renal Physiol. (2001) [Pubmed]
Quantitative EEG effects of carbamazepine, oxcarbazepine, valproate, lamotrigine, and possible clinical relevance of the findings. Clemens, B., Ménes, A., Piros, P., Bessenyei, M., Altmann, A., Jerney, J., Kollár, K., Rosdy, B., Rózsavölgyi, M., Steinecker, K., Hollódy, K. Epilepsy Res. (2006) [Pubmed]

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